Evidence map›Paper›PMID 27212084›Full record

ArticleThe Journal of allergy and clinical immunology2016

IL-1β enhances inflammatory TH2 differentiation.

Stephan M Caucheteux, Jane Hu-Li, Liying Guo, Nisan Bhattacharyya, Michelle Crank, Michael T Collins, William E Paul

Abstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Mgl2Nature communications · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Radiation-Detoxified Form of Endotoxin Effectively Activates ThInternational journal of molecular sciences · 2024
    Article
  15. T helper 2 cells in asthma.The Journal of experimental medicine · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Pneumococcal ΔJournal of microbiology and biotechnology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephan M CaucheteuxLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, and Division of Intramural Research, National Institutes of Health, Bethesda, Md. Electronic address: caucheteuxs@cardiff.ac.uk.
Jane Hu-LiLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, and Division of Intramural Research, National Institutes of Health, Bethesda, Md.
Liying GuoLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, and Division of Intramural Research, National Institutes of Health, Bethesda, Md.
Nisan BhattacharyyaNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Md.
Michelle CrankLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, and Division of Intramural Research, National Institutes of Health, Bethesda, Md; Viral Pathogenesis Laboratory, Vaccine Research Center, National Institutes of Health, Bethesda, Md.
Michael T CollinsNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Md.
William E PaulLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, and Division of Intramural Research, National Institutes of Health, Bethesda, Md.

Funding

Skeletal Disorders and Mineral Homeostasis SectionZIADE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 2009 to 2025
$32.8M
Interleukin 4ZIAAI000493 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GERMAIN, RONALD N · 2009 to 2017
$11.5M
INTERLEUKIN 4 (IL-4)Z01AI000493 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI PAUL, WILLIAM · 1987 to 2008
$3.1M
Intramural NIH HHS Z01 AI000493
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCD4-Positive T-LymphocytesCell DifferentiationImmunoglobulin EInflammationInterleukin-1betaInterleukin-4Interleukin-5MiceMice, Inbred BALB CMice, Inbred C57BLReceptors, Interleukin-1 Type ITh2 CellsImmunoglobulin EInterleukin-1betaInterleukin-4Interleukin-5Receptors, Interleukin-1 Type I

Identifiers

PMID27212084
PMCPMC5014664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.