ArticleJournal of substance abuse treatment2016
Gender Differences in Internalizing Symptoms and Suicide Risk Among Men and Women Seeking Treatment for Cannabis Use Disorder from Late Adolescence to Middle Adulthood.
Article in Journal of substance abuse treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Sex differences in the acute effects of smoked cannabis: evidence from a human laboratory study of young adults.Psychopharmacology · 2020Trial
- The Concise Health Risk Tracking-Self Report: Psychometrics within a placebo-controlled antidepressant trial among depressed outpatients.Journal of psychopharmacology (Oxford, England) · 2019Trial
- Global burden and trends of depression among women of childbearing age, 1990-2021.Public health in practice (Oxford, England) · 2026Article
- Adolescent with cannabis use disorder and other mental health disorders: does dual disorder worsen school impairment?Journal of cannabis research · 2026Article
- Differential associations of mental health, mild traumatic brain injury and substance use between male and female university students.PloS one · 2026Article
- Gender Differences in Cannabis as a Mediator Between Distress Factors and Non-Fatal Suicidal Behaviors.International journal of mental health and addiction · 2025Article
- Longitudinal Links Between Vicarious Racism and Mental Health Among Mexican-Origin Adolescents: The Moderating Role of Daily Sleep Quality.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Melanin-Concentrating Hormone (MCH): Role in Mediating Reward-Motivated and Emotional Behavior and the Behavioral Disturbances Produced by Repeated Exposure to Reward Substances.International journal of molecular sciences · 2025Review
- Gender differences in circumstances associated with cannabis use.The American journal on addictions · 2025Article
- Internalizing symptoms, negative urgency, and coping motives: Potential pathways to alcohol consequences.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
- Examining time-varying dynamics of co-occurring depressed mood and anxiety.Journal of affective disorders · 2024Article
- Neurological Disorders Induced by Drug Use: Effects of Adolescent and Embryonic Drug Exposure on Behavioral Neurodevelopment.International journal of molecular sciences · 2024Review
- Developmental trajectories of alcohol and cannabis concurrent use in a nationally representative sample of United States youths.Drug and alcohol dependence · 2023Article
- Sex differences in the subjective and reinforcing effects of smoked cannabis.Addiction biology · 2023Article
- An exploratory follow-up study of cannabis use and decision-making under various risk conditions within adolescence.Neuropsychology · 2023Article
- Risky cannabis use is associated with varying modes of cannabis consumption: Gender differences among Canadian high school students.Drug and alcohol dependence reports · 2022Article
- Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence.Psychopharmacology · 2022Review
- Gender Differences in Dual Diagnoses Associated with Cannabis Use: A Review.Brain sciences · 2022Review
- The estimand framework and its application in substance use disorder clinical trials: a case study.The American journal of drug and alcohol abuse · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Cannabis continues to rise in popularity as the perception of its harmfulness decreases and evidence of its deleterious developmental effect increases. While internalizing distress and suicide risk have been linked with cannabis use problems [DSM-5 cannabis use disorder (CUD); DSM-IV cannabis abuse and dependence] it remains unclear how this association varies over the course of development in treatment-seeking men and women. The current study utilized the National Drug Abuse Treatment Clinical Trials Network (NIDA CTN) to conduct a cross-sectional comparison of internalizing distress and suicide risk among men (n=437) and women (n=163) spanning ages 18-50 who met DSM-5 criteria for CUD. Interactions between gender and developmental stage (i.e., late adolescence, early adulthood, and middle adulthood) were observed for suicide risk and anxiety but not depression problems. Specifically, women seeking CUD treatment in late adolescence and middle adulthood exhibited significantly higher rates of anxiety and suicide risk compared to men seeking treatment during the same developmental stages. Internalizing distress and suicide risk did not differ between treatment-seeking men and women in the early adult stage. Overall, results suggest that the structure of risk for CUD may differ in men and women across the lifespan and that women presenting for CUD treatment during late adolescence and middle adulthood may uniquely benefit from intervention designed to address these elevations in anxiety and suicide risk.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.