ReviewNeuroscience and biobehavioral reviews2016
Different involvement of subregions within dorsal premotor and medial frontal cortex for pro- and antisaccades.
Review in Neuroscience and biobehavioral reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Transdiagnostic eye-tracking biomarkers of inattention across psychiatric disorders: a systematic review.BMC psychiatry · 2025Pooled it
- Accurate localization and coactivation profiles of the frontal eye field and inferior frontal junction: an ALE and MACM fMRI meta-analysis.Brain structure & function · 2023Pooled it
- Risk-taking in the human brain: An activation likelihood estimation meta-analysis of the balloon analog risk task (BART).Human brain mapping · 2022Pooled it
- Delineating visual, auditory and motor regions in the human brain with functional neuroimaging: a BrainMap-based meta-analytic synthesis.Scientific reports · 2021Pooled it
- Meta-analytic evidence for a core problem solving network across multiple representational domains.Neuroscience and biobehavioral reviews · 2018Pooled it
- Gray matter asymmetries in aging and neurodegeneration: A review and meta-analysis.Human brain mapping · 2017Pooled it
- Neural signatures of trust in reciprocity: A coordinate-based meta-analysis.Human brain mapping · 2017Pooled it
- GABAergic Modulation of Brain Function During Prosaccade and Antisaccade Eye Movements: Evidence From Ultra-High-Field fMRI.Human brain mapping · 2026Trial
- Exploring eye movement abnormalities as objective biomarkers for Parkinson's disease utilizing virtual reality-based eye tracking.BMC neurology · 2026Article
- Revised cytoarchitectonic mapping of the human premotor cortex identifies seven areas and refines the localisation of frontal eye fields.Communications biology · 2025Article
- Vestibular Well-Being Benefits of a Single Session of Functional Neurology Intervention on Saccadic Stimuli Dysfunction.Healthcare (Basel, Switzerland) · 2025Article
- Cognitive control in individuals with heroin use disorder after prolonged methadone maintenance treatment.BMC psychiatry · 2025Article
- Exploring oculomotor functions in a pilot study with healthy controls: Insights from eye-tracking and fMRI.PloS one · 2024Article
- Application and progress of advanced eye movement examinations in cognitive impairment.Frontiers in aging neuroscience · 2024Review
- The functional connectome of 3,4-methyldioxymethamphetamine-related declarative memory impairments.Human brain mapping · 2023Article
- Neural mechanisms of background and velocity effects in smooth pursuit eye movements.Human brain mapping · 2023Article
- Interhemispheric co-alteration of brain homotopic regions.Brain structure & function · 2021Article
- Structure, function and connectivity fingerprints of the frontal eye field versus the inferior frontal junction: A comprehensive comparison.The European journal of neuroscience · 2021Review
- Age differences in predicting working memory performance from network-based functional connectivity.Cortex; a journal devoted to the study of the nervous system and behavior · 2020Article
- The intersection between the oculomotor and hippocampal memory systems: empirical developments and clinical implications.Annals of the New York Academy of Sciences · 2020Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
The antisaccade task has been widely used to investigate cognitive action control. While the general network for saccadic eye movements is well defined, the exact location of eye fields within the frontal cortex strongly varies between studies. It is unknown whether this inconsistency reflects spatial uncertainty or is the result of different involvement of subregions for specific aspects of eye movement control. The aim of the present study was to examine functional differentiations within the frontal cortex by integrating results from neuroimaging studies analyzing pro- and antisaccade behavior using meta-analyses. The results provide evidence for a differential functional specialization of neighboring oculomotor frontal regions, with lateral frontal eye fields (FEF) and supplementary eye field (SEF) more often involved in prosaccades while medial FEF and anterior midcingulate cortex (aMCC) revealed consistent stronger involvement for antisaccades. This dissociation was furthermore mirrored by functional connectivity analyses showing that the lateral FEF and SEF are embedded in a motor output network, while medial FEF and aMCC are integrated in a multiple demand network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.