Evidence map›Paper›PMID 27209606›Full record

ArticleThe Annals of thoracic surgery2016

The Society of Thoracic Surgeons Lung Cancer Resection Risk Model: Higher Quality Data and Superior Outcomes.

Felix G Fernandez, Andrzej S Kosinski, William Burfeind, Bernard Park, Malcolm M DeCamp, Christopher Seder, Blair Marshall, Mitchell J Magee, Cameron D Wright, Benjamin D Kozower

Erratum issuedAbstract readMulticenter StudyVideo-Audio Media
In one paragraph

Article in The Annals of thoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 95 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  16. Minimally invasive surgery for clinical T4 non-small-cell lung cancer: national trends and outcomes.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
    Article
  17. The relation of body adiposity to the outcomes of thoracoscopic lobectomy for lung cancer - a single-center cohort study.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2024
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Felix G FernandezEmory University, Atlanta, Georgia. Electronic address: felix.fernandez@emoryhealthcare.org.
Andrzej S KosinskiDuke Clinical Research Institute, Durham, North Carolina.
William BurfeindSt. Luke's Health Network, Allentown, Pennsylvania.
Bernard ParkMemorial Sloan Kettering Cancer Center, New York, New York.
Malcolm M DeCampNorthwestern University, Chicago, Illinois.
Christopher SederRush University, Chicago, Illinois.
Blair MarshallGeorgetown University, Washington, DC.
Mitchell J MageeMedical City Hospital, Dallas, Texas.
Cameron D WrightMassachusetts General Hospital, Boston, Massachusetts.
Benjamin D KozowerUniversity of Virginia, Charlottesville, Virginia.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
National Longitudinal Outcomes Following Surgical Therapy for Lung CancerR01HS022279 · AHRQ · SOCIETY OF THORACIC SURGEONS · PI FERNANDEZ, FELIX GABRIEL · 2014 to 2017
$986k
AHRQ HHS R01 HS022279NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA060553
6 · The paper itself

Abstract

backgroundThe Society of Thoracic Surgeons (STS) creates risk-adjustment models for common cardiothoracic operations for quality improvement purposes. Our aim was to update the lung cancer resection risk model utilizing the STS General Thoracic Surgery Database (GTSD) with a larger and more contemporary cohort.

methodsWe queried the STS GTSD for all surgical resections of lung cancers from January 1, 2012, through December 31, 2014. Logistic regression was used to create three risk models for adverse events: operative mortality, major morbidity, and composite mortality and major morbidity.

resultsIn all, 27,844 lung cancer resections were performed at 231 centers; 62% (n = 17,153) were performed by thoracoscopy. The mortality rate was 1.4% (n = 401), major morbidity rate was 9.1% (n = 2,545), and the composite rate was 9.5% (n = 2,654). Predictors of mortality included age, being male, forced expiratory volume in 1 second, body mass index, cerebrovascular disease, steroids, coronary artery disease, peripheral vascular disease, renal dysfunction, Zubrod score, American Society of Anesthesiologists rating, thoracotomy approach, induction therapy, reoperation, tumor stage, and greater extent of resection (all p < 0.05). For major morbidity and the composite measure, cigarette smoking becomes a risk factor whereas stage, renal dysfunction, congestive heart failure, and cerebrovascular disease lose significance.

conclusionsOperative mortality and complication rates are low for lung cancer resection among surgeons participating in the GTSD. Risk factors from the prior lung cancer resection model are refined, and new risk factors such as prior thoracic surgery are identified. The GTSD risk models continue to evolve as more centers report and data are audited for quality assurance.

Indexed as

Models, StatisticalSocieties, MedicalThoracic SurgeryAgedAge FactorsFemaleHumansIncidenceLung NeoplasmsMalePneumonectomyPostoperative ComplicationsRisk AdjustmentRisk FactorsSex FactorsSurvival Rate

Identifiers

PMID27209606
PMCPMC5016798

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.