ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2016
The effects of extracellular contrast agent (Gadobutrol) on the precision and reproducibility of cardiovascular magnetic resonance feature tracking.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Beyond volumes and ejection fraction: practical insights into cine-CMR interpretation and applications.The international journal of cardiovascular imaging · 2025Review
- The effects of flip angle and gadolinium contrast agent on single breath-hold compressed sensing cardiac magnetic resonance cine for biventricular global strain assessment.Frontiers in cardiovascular medicine · 2024Article
- Comparison between pre- and post-contrast cardiac MRI cine images: the impact on ventricular volume and strain measurement.The international journal of cardiovascular imaging · 2023Article
- Impact of Right Ventricular Trabeculation on Right Ventricular Function in Patients With Left Ventricular Non-compaction Phenotype.Frontiers in cardiovascular medicine · 2022Article
- Left ventricular characteristics of noncompaction phenotype patients with good ejection fraction measured with cardiac magnetic resonance.Anatolian journal of cardiology · 2021Article
- Comparison between conventional and compressed sensing cine cardiovascular magnetic resonance for feature tracking global circumferential strain assessment.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Left ventricular global myocardial strain assessment: Are CMR feature-tracking algorithms useful in the clinical setting?La Radiologia medica · 2020Article
- Feature-tracking-based strain analysis - a comparison of tracking algorithms.Polish journal of radiology · 2020Article
- The effect of contrast agents on left ventricular parameters calculated by a threshold-based software module: does it truly matter?The international journal of cardiovascular imaging · 2019Article
- Journal of Cardiovascular Magnetic Resonance 2017.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018Review
- Left ventricular global myocardial strain assessment comparing the reproducibility of four commercially available CMR-feature tracking algorithms.European radiology · 2018Article
- Influence of observer experience on cardiac magnetic resonance strain measurements using feature tracking and conventional tagging.International journal of cardiology. Heart & vasculature · 2018Article
- Review of Journal of Cardiovascular Magnetic Resonance (JCMR) 2015-2016 and transition of the JCMR office to Boston.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017Review
- Cardiovascular magnetic resonance myocardial feature tracking using a non-rigid, elastic image registration algorithm: assessment of variability in a real-life clinical setting.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017Article
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7 authors.
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Abstract
backgroundToday feature tracking (FT) is considered to be a robust assessment tool in cardiovascular magnetic resonance (CMR) for strain assessment. The FT algorithm is dependent on a high contrast between blood pool and myocardium. Extracellular contrast agents decrease blood-myocardial contrast in SSFP images and thus might affect FT results. However, in a routine CMR scan, SSFP-cine images including short axis views are partly acquired after contrast agent injection. The aim of this study was to investigate the effect of extracellular contrast agent (Gadobutrol) (CA) on the precision and reproducibility of the feature tracking algorithm.
methodsA total of 40 patient volunteers (mean age 51.2 ± 19 years; mean LVEF 61 ± 9 %) were scanned in supine position on a clinical 1.5 T MR scanner (Philips Ingenia). SSFP-cine images in midventricular short axis view (SA) as well as horizontal long axis view (HLA) were acquired before and 10-15 min after injection of a double dose Gadobutrol. FT derived systolic circumferential and longitudinal strain parameters were then calculated for pre- and post-contrast images.
resultsFT derived midventricular peak systolic circumferential strain (PSCS) (-24.8 ± 6.4 % vs. -20.4 ± 6.3 %), apical PSCS (-28.67 ± 6.5 % vs. -24.06 ± 8.5 %), basal PSCS (-24.42 % ± 6.5 vs. -20.68 ± 7.1 %), peak systolic longitudinal strain (-19.57 ± 3.3 % vs. -17.24 ± 4.1 %), midventricular epicardial PSCS (-9.84 ± 3.4 % vs. -8.13 ± 3.4 %) , midventricular PSCS-rate (-1.52 ± 0.4 vs. -1.28 ± 0.5) and peak diastolic circumferential strain rate (1.4 ± 0.5 vs. 1.05 ± 0.5) were significantly reduced after CA application. Post CA strain assessment showed higher intra- and interobserver variability. Pre-CA: intraobserver: mean 0.21, Limits of agreement (LoA) -2.8 and 3.2; interobserver: mean 0.64, LoA -2.8 and 4.1. Post-CA: intraobserver: mean -0.11, LoA -5.1 to 4.9; interobserver: mean 4.93 LoA 2.4 to 12.2.
conclusionThe FT algorithm is dependent on a high contrast between blood and myocardium. Post CA strain results are significantly lower and less reproducible than pre-CA strain results.
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