ArticleBMC infectious diseases2016
Chronic Cystoisospora belli infection in an immunocompetent Myanmar refugee - microscopy is not sensitive enough.
Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Cystoisospora belli infection in an immunocompetent patient.Parasitology research · 2026Article
- Article
- Life Cycle and Transmission ofMicroorganisms · 2022Review
- Intestinal apicomplexan parasitoses among a hospital-based population in Honduras, 2013-2019.Biomedica : revista del Instituto Nacional de Salud · 2021Article
- Case Report: Molecular Diagnosis of Cystoisospora belli in a Severely Immunocompromised Patient with HIV and Kaposi Sarcoma.The American journal of tropical medicine and hygiene · 2021Article
- Molecular detection of Cystoisospora belli by single-run polymerase chain reaction in stool samples.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- Comparison of Two Real-Time PCR Assays Targeting Ribosomal Sequences for the Identification ofPathogens (Basel, Switzerland) · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCystoisosporiasis is an opportunistic infection seen more commonly in patients with acquired immunodeficiency syndrome. Although uncommon, Cystoisospora infection can occur in immunocompetent individuals but tend to be benign and self-limiting. Chronic infection however, has been described but diagnosis can often be challenging and requires a high clinical index of suspicion. CASE PRESENTATION: We present a case of delayed diagnosis of Cystoisospora belli (C. belli) in an immunocompetent 28-year-old refugee from Myanmar. She had a history of chronic diarrhea where exhaustive investigations over many years failed to reveal a diagnosis. Cystoisospora belli cysts were finally detected in stool 4 years after investigation commenced, and PCR testing on stored colon biopsies amplified a molecular product with 99 % sequence homology to C. belli. The patient improved promptly with trimethoprim-sulfamethoxazole treatment.
conclusionIn the appropriate clinical context we suggest molecular testing for C. belli or an empirical therapeutic trial.
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Registered trials
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