ArticleRevista brasileira de hematologia e hemoterapia
Oral health-related quality of life of children and teens with sickle cell disease.
Article in Revista brasileira de hematologia e hemoterapia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 13 citations in OpenAlex.
- Oral health and quality of life in children with blood coagulation disorders and hemoglobinopathies. A cross-sectional study.Journal of family medicine and primary care · 2025Article
- Oral health-related quality of life determinants throughout adolescence: a cohort study in Brazil.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Malocclusion traits and oral health-related quality of life in children with osteogenesis imperfecta: A cross-sectional study.Journal of the American Dental Association (1939) · 2020Article
- Oral health-related quality of life in children and adolescents with osteogenesis imperfecta: cross-sectional study.Orphanet journal of rare diseases · 2018Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildren with sickle cell disease may have their quality of life affected by oral alterations. However, there is still little data on oral health-related quality of life in these children. The aim of this study was to investigate the influence of sickle cell disease, socioeconomic characteristics, and oral conditions on oral health-related quality of life of children and teens.
methodOne hundred and six children and teens with sickle cell disease were compared to a similar sample of 385 healthy peers. Data were collected through oral examinations, interviews to assess quality of life (Child Perceptions Questionnaire for children aged 8-10 and 11-14) and questionnaires containing questions on socioeconomic status.
resultsThere were no statistically significant differences in the total scores of the Child Perceptions Questionnaires or domain scores comparing sickle cell disease patients to control subjects. When sub-scales were compared, oral symptoms and functional limitations had a greater negative impact on the quality of life of adolescents with sickle cell disease (p-value <0.001 and p-value <0.01, respectively) when compared to healthy controls. The only statistically significant determinants of negative impact on oral health-related quality of life in the overall sample was home overcrowding (more than two people/room) in the younger children's group, and dental malocclusion among teens.
conclusionThere was no significant difference in the negative impact on the oral health-related quality of life between the group with sickle cell disease and the control group. Of the oral alterations, there was a significant difference in the oral health-related quality of life between adolescents with sickle cell disease and controls only in relation to malocclusion. Among the socioeconomic characteristics, only overcrowding was significantly associated with a negative impact on oral health-related quality of life.
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