Evidence map›Paper›PMID 27208515›Full record

ArticleThe Journal of urology2016

Determinants of Survival for Adolescents and Young Adults with Urothelial Bladder Cancer: Results from the California Cancer Registry.

Joshua Lara, Ann Brunson, Theresa H M Keegan, Marcio Malogolowkin, Chong-Xian Pan, Stanley Yap, Ralph deVere White

Open access · greenAbstract readComparative Study
In one paragraph

Article in The Journal of urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Survival Trends Among Adolescents and Young Adults Diagnosed With Cancer in the United States: Comparisons With Children and Older Adults.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
  6. Long-Term Outcomes among Adolescent and Young Adult Survivors of Acute Leukemia: A Surveillance, Epidemiology, and End Results Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  7. Article
  8. Prognostic Factors for Bladder Cancer Patients in Malaysia: A Population-Based Study.International journal of environmental research and public health · 2022
    Article
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  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joshua LaraDavis Senior High School, Davis, California.
Ann BrunsonUniversity of California Davis Comprehensive Cancer Center, Sacramento, California.
Theresa H M KeeganUniversity of California Davis Comprehensive Cancer Center, Sacramento, California.
Marcio MalogolowkinUniversity of California Davis Comprehensive Cancer Center, Sacramento, California.
Chong-Xian PanUniversity of California Davis Comprehensive Cancer Center, Sacramento, California.
Stanley YapUniversity of California Davis Comprehensive Cancer Center, Sacramento, California.
Ralph deVere WhiteUniversity of California Davis Comprehensive Cancer Center, Sacramento, California. Electronic address: rwdeverewhite@ucdavis.edu.
University of California, Davis · USUC Davis Comprehensive Cancer Center

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI PRIMO N. LARA · 2002 to 2026
$84.9M
NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

purposeBladder cancer is a common malignancy often diagnosed in older adults. Previous studies have reported racial/ethnic disparities in bladder cancer survival outcomes but have not focused on younger patients. We identified whether factors influencing cause specific survival in adolescents and young adults (ages 15 to 39) differed from older adults, and defined prognostic factors specifically in adolescents and young adults using the California Cancer Registry. MATERIALS AND

methodsPatients diagnosed with bladder cancer between 1988 through 2012 were included in the study. The primary outcome measure was cause specific survival. A multivariable Cox proportional hazards regression model was used to evaluate predictors of cause specific survival in patients of all ages and in adolescents/young adults. Interactions of age and other variables between younger and older adult patients were assessed.

resultsOf 104,974 patients with bladder cancer we identified 1,688 adolescent and young adult patients (1.6%). Compared to older patients these patients had a 58% reduced risk of bladder cancer death (HR 0.42, p <0.001). Significant age interactions were identified involving race/ethnicity and histology. Among adolescents and young adults, nonHispanic African-American patients with low socioeconomic status had poor cause specific (HR 7.1, p <0.001) and overall (HR 5.02, p <0.001) survival.

conclusionsRacial/ethnic and socioeconomic disparities exist in adolescent and young adult patients with bladder cancer in California. Further studies are warranted to identify the underlying causes in order to overcome these disparities.

Indexed as

AdolescentAdultAge FactorsCaliforniaCarcinoma, Transitional CellFemaleHealth Status DisparitiesHumansMaleRegistriesSurvival RateUrinary Bladder NeoplasmsYoung Adultadolescentepidemiologyhealth status disparitiesurinary bladder neoplasmsyoung adult

Identifiers

PMID27208515
PMCPMC5319865
OpenAlexW2408438958

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.