Evidence map›Paper›PMID 27208330›Full record

ArticleDiabetes care2016

Differences in Hemoglobin A1c Between Hispanics/Latinos and Non-Hispanic Whites: An Analysis of the Hispanic Community Health Study/Study of Latinos and the 2007-2012 National Health and Nutrition Examination Survey.

M Larissa Avilés-Santa, Lucy L Hsu, Mario Arredondo, Andy Menke, Ellen Werner, Bharat Thyagarajan, Gerardo Heiss, Yanping Teng, Neil Schneiderman, Aida L Giachello and 3 more

Abstract read
In one paragraph

Article in Diabetes care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  11. Sex-Specific Associations of Iron-Anemia Status With Hemoglobin A1C Levels Among Hispanics/Latinos Without Self-Reported Diabetes Mellitus: The Hispanic Community Health Study/Study of Latinos.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Article
  12. Article
  13. Pervasive structural racism in environmental epidemiology.Environmental health : a global access science source · 2021
    Article
  14. Observational
  15. Article
  16. Article
  17. Objectively measured sedentary time, physical activity and liver enzyme elevations in US Hispanics/Latinos.Liver international : official journal of the International Association for the Study of the Liver · 2020
    Article
  18. The Oral Glucose Tolerance Test: 100 Years Later.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

M Larissa Avilés-SantaDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD avilessantal@nhlbi.nih.gov.
Lucy L HsuDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Mario ArredondoColumbia University Mailman School of Public Health, New York, NY.
Andy MenkeSocial & Scientific Systems, Inc., Silver Spring, MD.
Ellen WernerDivision of Blood Diseases and Resources, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Bharat ThyagarajanDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.
Gerardo HeissCollaborative Studies Coordinating Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Yanping TengCollaborative Studies Coordinating Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Neil SchneidermanMiller School of Medicine, University of Miami, Miami, FL.
Aida L GiachelloNorthwestern University Feinberg School of Medicine, Chicago, IL.
Linda C GalloDepartment of Psychology, San Diego State University, San Diego, CA.
Gregory A TalaveraInstitute for Behavioral and Community Health, Graduate School of Public Health, San Diego State University, San Diego, CA.
Catherine C CowieNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

Funding

Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237
6 · The paper itself

Abstract

objectiveTo determine whether, after adjustment for glycemia and other selected covariates, hemoglobin A1c (HbA1c) differed among adults from six Hispanic/Latino heritage groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) and between Hispanic/Latino and non-Hispanic white adults without self-reported diabetes. RESEARCH DESIGN AND

methodsWe performed a cross-sectional analysis of data from 13,083 individuals without self-reported diabetes from six Hispanic/Latino heritage groups, enrolled from 2008 to 2011 in the Hispanic Community Health Study/Study of Latinos, and 2,242 non-Hispanic white adults enrolled during the 2007-2012 cycles of the National Health and Nutrition Examination Survey. We compared HbA1c levels among Hispanics/Latinos and between Hispanics/Latinos and non-Hispanic whites before and after adjustment for age, sex, fasting (FPG) and 2-h post-oral glucose tolerance test (2hPG) glucose, anthropometric measurements, and selected biochemical and hematologic variables and after stratification by diabetes status: unrecognized diabetes (FPG ≥7.1 mmol/L or 2hPG ≥11.2 mmol/L), prediabetes (FPG 5.6-7.0 mmol/L or 2hPG 7.8-11.1 mmol/L), and normal glucose tolerance (FPG <5.6 mmol/L and 2hPG <7.8 mmol/L).

resultsAdjusted mean HbA1c differed significantly across all seven groups (P < 0.001). Non-Hispanic whites had significantly lower HbA1c (P < 0.05) than each individual Hispanic/Latino heritage group. Upon stratification by diabetes status, statistically significant differences (P < 0.001) in adjusted mean HbA1c persisted across all seven groups.

conclusionsHbA1c differs among Hispanics/Latinos of diverse heritage groups and between non-Hispanic whites and Hispanics/Latinos after adjustment for glycemia and other covariates. The clinical significance of these differences is unknown.

Indexed as

Hispanic or LatinoWhite PeopleAdultBlood GlucoseCentral AmericaCross-Sectional StudiesCubaDiabetes MellitusFastingFemaleGlucose Tolerance TestGlycated HemoglobinHumansMaleMexican AmericansMexicoBlood GlucoseGlycated Hemoglobin

Identifiers

PMID27208330
PMCPMC5317242

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.