ArticlePlant physiology2016
The WD-Repeat Protein CsTTG1 Regulates Fruit Wart Formation through Interaction with the Homeodomain-Leucine Zipper I Protein Mict.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 62 citations in OpenAlex.
- A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber.Plant biotechnology journal · 2026Article
- ENHANCER OF SHOOT REGENERATION 1 (ESR1) functions in trichome initiation in cucumber (Cucumis sativus L.).The Plant journal : for cell and molecular biology · 2026Article
- Exploring the jasmonic acid signaling pathway: the role ofHorticulture research · 2026Article
- Integrated transcriptomic and metabolomic analysis reveals the regulatory role of lignin biosynthesis in raspberry (Rubus niveus) prickle development.BMC plant biology · 2026Article
- Nature's Shield: Exploring Nonglandular Trichomes (NGT) as Key Players in Plant Defense Mechanisms.Plant direct · 2025Review
- McATL43 encoding a RING-H2 finger E3 ubiquitin ligase is responsible for Shark teeth (St) fruit wart in bitter gourd (Momordica charantia L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- The role, regulation and application of plant fruit trichomes.Molecular horticulture · 2025Review
- Construction of the super pan-genome for the genusHorticulture research · 2025Article
- The CsTM alters multicellular trichome morphology and enhances resistance against aphid by interacting with CsTIP1;1 in cucumber.Journal of advanced research · 2025Article
- Mining the cucumber core collection: phenotypic and genetic characterization of morphological diversity for fruit quality characteristics.Horticulture research · 2025Article
- Mutations in a Leucine-Rich Repeat Receptor-Like Kinase gene result in male sterility and reduction in the number and size of fruit warts in cucumber (Cucumis sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genome-Wide Identification and Analysis of WD40 Family and Its Expression inInternational journal of molecular sciences · 2024Article
- CsTs, a C-type lectin receptor-like kinase, regulates the development trichome development and cuticle metabolism in cucumber (Horticulture research · 2024Article
- The WUSCHEL-related homeobox transcription factorHorticulture research · 2024Article
- CucumberAI: Cucumber Fruit Morphology Identification System Based on Artificial Intelligence.Plant phenomics (Washington, D.C.) · 2024Article
- Beyond skin-deep: targeting the plant surface for crop improvement.Journal of experimental botany · 2023Review
- Advances in understanding epigenetic regulation of plant trichome development: a comprehensive review.Horticulture research · 2023Article
- Review
- Identification and Functional Characterization ofInternational journal of molecular sciences · 2023Article
- Melon yellow-green plant (Cmygp) encodes a Golden2-like transcription factor regulating chlorophyll synthesis and chloroplast development.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cucumber (Cucumis sativus) fruit is covered with bloom trichomes and warts (composed of spines and tubercules), which have an important impact on the commercial value of the crop. However, little is known about the regulatory mechanism underlying their formation. Here, we reported that the cucumber WD-repeat homolog CsTTG1, which is localized in the nucleus and cytomembrane, plays an important role in the formation of cucumber fruit bloom trichomes and warts. Functional characterization of CsTTG1 revealed that it is mainly expressed in the epidermis of cucumber ovary and that its overexpression in cucumber alters the density of fruit bloom trichomes and spines, thereby promoting the warty fruit trait. Conversely, silencing CsTTG1 expression inhibits the initiation of fruit spines. Molecular and genetic analyses showed that CsTTG1 acts in parallel to Mict/CsGL1, a key trichome formation factor, to regulate the initiation of fruit trichomes, including fruit bloom trichomes and spines, and that the further differentiation of fruit spines and formation of tubercules regulated by CsTTG1 is dependent on Mict Using yeast two-hybrid assay and bimolecular fluorescence complementation assay, we determined that CsTTG1 directly interacts with Mict. Collectively, our results indicate that CsTTG1 is an important component of the molecular network that regulates fruit bloom trichome and wart formation in cucumber.
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