Evidence map›Paper›PMID 27208287›Full record

ArticlePlant physiology2016

Albino Leaf1 That Encodes the Sole Octotricopeptide Repeat Protein Is Responsible for Chloroplast Development.

Zemin Zhang, Jianjie Tan, Zhenying Shi, Qingjun Xie, Yi Xing, Changhong Liu, Qiaoling Chen, Haitao Zhu, Jiang Wang, Jingliu Zhang and 1 more

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Chlorophyll deficient 5 encodes a DNA helicase and is essential for chloroplast development in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Function of ALA Content in Porphyrin Metabolism Regulation ofInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Exon skipping inFrontiers in plant science · 2022
    Article
  11. Article
  12. Article
  13. Transformation of Long-Lived AlbinoFrontiers in plant science · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zemin ZhangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.) zmzhang@scau.edu.cn gqzhang@scau.edu.cn.ORCID 0000-0002-5510-8508
Jianjie TanState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).
Zhenying ShiState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).ORCID 0000-0002-8441-2162
Qingjun XieState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).ORCID 0000-0002-6372-3260
Yi XingState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).
Changhong LiuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).
Qiaoling ChenState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).
Haitao ZhuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).
Jiang WangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).
Jingliu ZhangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.).
Guiquan ZhangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Provincial Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou 510642, China (Z.Z., J.T., Q.X., Y.X., C.L., Q.C., H.Z., G.Z.); andShanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 20032, China (Z.S., J.W., J.Z.) zmzhang@scau.edu.cn gqzhang@scau.edu.cn.
South China Agricultural University · CNChinese Academy of Sciences · CNCenter for Excellence in Molecular Plant Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chloroplast, the photosynthetic organelle in plants, plays a crucial role in plant development and growth through manipulating the capacity of photosynthesis. However, the regulatory mechanism of chloroplast development still remains elusive. Here, we characterized a mutant with defective chloroplasts in rice (Oryza sativa), termed albino leaf1 (al1), which exhibits a distinct albino phenotype in leaves, eventually leading to al1 seedling lethality. Electronic microscopy observation demonstrated that the number of thylakoids was reduced and the structure of thylakoids was disrupted in the al1 mutant during rice development, which eventually led to the breakdown of chloroplast. Molecular cloning revealed that AL1 encodes the sole octotricopeptide repeat protein (RAP) in rice. Genetic complementation of Arabidopsis (Arabidopsis thaliana) rap mutants indicated that the AL1 protein is a functional RAP. Further analysis illustrated that three transcript variants were present in the AL1 gene, and the altered splices occurred at the 3' untranslated region of the AL1 transcript. In addition, our results also indicate that disruption of the AL1 gene results in an altered expression of chloroplast-associated genes. Consistently, proteomic analysis demonstrated that the abundance of photosynthesis-associated proteins is altered significantly, as is that of a group of metabolism-associated proteins. More specifically, we found that the loss of AL1 resulted in altered abundances of ribosomal proteins, suggesting that RAP likely also regulates the homeostasis of ribosomal proteins in rice in addition to the ribosomal RNA. Taken together, we propose that AL1, particularly the AL1a and AL1c isoforms, plays an essential role in chloroplast development in rice.

Indexed as

Repetitive Sequences, Amino AcidChloroplastsCloning, MolecularGene Expression Regulation, PlantGenes, PlantMutationPhenotypePhotosynthesisPlant ProteinsRibosomesRNA, MessengerRNA Processing, Post-TranscriptionalRNA, Ribosomal, 16SThylakoidsPlant ProteinsRNA, MessengerRNA, Ribosomal, 16S

Identifiers

PMID27208287
PMCPMC4902615
OpenAlexW2338405772

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.