ArticlePlant physiology2016
Characterization of a New Pink-Fruited Tomato Mutant Results in the Identification of a Null Allele of the SlMYB12 Transcription Factor.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 61 citations in OpenAlex.
- Developing new tomato lines in Indigo Rose genetic background with differential anthocyanin and carotenoid production in fruits.Frontiers in plant science · 2026Article
- Integrated widely-targeted metabolome and transcriptome analysis provide novel insights into the regulation of nutritional formation inFrontiers in plant science · 2026Article
- MYB regulator of "colorless" flavonols underlies the evolution of red flowers in Iochroma (Solanaceae).G3 (Bethesda, Md.) · 2025Article
- SlBES1-mediated brassinosteroid signaling suppresses flavonoid biosynthesis in tomato fruit.Plant communications · 2025Article
- CmVNI2-CmMYB3 module regulates flavonol biosynthesis in response to low temperature in chrysanthemum flower.Molecular horticulture · 2025Article
- CRISPR-Cas9: Unraveling Genetic Secrets to Enhance Floral and Fruit Traits in Tomato.Molecular biotechnology · 2025Review
- Spatial metabolic heterogeneity of sugar-acid balance and pigment accumulation in distinct color regions ofFrontiers in plant science · 2025Article
- Mapping and transcriptomic profiling reveal that the KNAT6 gene is involved in the dark green peel colour of mature pumpkin fruit (Cucurbita maxima L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Transcriptional regulation of flavonol biosynthesis in plants.Horticulture research · 2024Review
- Recent Advances in Tomato Gene Editing.International journal of molecular sciences · 2024Review
- Combined Widely Targeted Metabolomic, Transcriptomic, and Spatial Metabolomic Analysis Reveals the Potential Mechanism of Coloration and Fruit Quality Formation inFoods (Basel, Switzerland) · 2024Article
- SlERF.G3-Like mediates a hierarchical transcriptional cascade to regulate ripening and metabolic changes in tomato fruit.Plant biotechnology journal · 2024Article
- An LcMYB111-LcHY5 Module Differentially Activates anInternational journal of molecular sciences · 2023Article
- Insight into the Molecular Mechanism of Flower Color Regulation inPlants (Basel, Switzerland) · 2023Article
- Genetics and breeding of phenolic content in tomato, eggplant and pepper fruits.Frontiers in plant science · 2023Review
- A comparative transcriptomics and eQTL approach identifies SlWD40 as a tomato fruit ripening regulator.Plant physiology · 2022Article
- ODORANT1 targets multiple metabolic networks in petunia flowers.The Plant journal : for cell and molecular biology · 2022Article
- The metabolic changes that effect fruit quality during tomato fruit ripening.Molecular horticulture · 2022Review
- Regulation of Tomato Specialised Metabolism after Establishment of Symbiosis with the Endophytic FungusMicroorganisms · 2022Article
- Modifying Anthocyanins Biosynthesis in Tomato Hairy Roots: A Test Bed for Plant Resistance to Ionizing Radiation and Antioxidant Properties in Space.Frontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The identification and characterization of new tomato (Solanum lycopersicum) mutants affected in fruit pigmentation and nutritional content can provide valuable insights into the underlying biology, as well as a source of new alleles for breeding programs. To date, all characterized pink-pigmented tomato fruit mutants appear to result from low SlMYB12 transcript levels in the fruit skin. Two new mutant lines displaying a pink fruit phenotype (pf1 and pf2) were characterized in this study. In the pf mutants, SlMYB12 transcripts accumulated to wild-type levels but exhibited the same truncation, which resulted in the absence of the essential MYB activation domain coding region. Allelism and complementation tests revealed that both pf mutants were allelic to the y locus and showed the same recessive null allele in homozygosis: Δy A set of molecular and metabolic effects, reminiscent of those observed in the Arabidopsis (Arabidopsis thaliana) myb11 myb12 myb111 triple mutant, were found in the tomato Δy mutants. To our knowledge, these have not been described previously, and our data support the idea of their being null mutants, in contrast to previously described transcriptional hypomorphic pink fruit lines. We detected a reduction in the expression of several flavonol glycosides and some associated glycosyl transferases. Transcriptome analysis further revealed that the effects of the pf mutations extended beyond the flavonoid pathway into the interface between primary and secondary metabolism. Finally, screening for Myb-binding sites in the candidate gene promoter sequences revealed that 141 of the 152 co-down-regulated genes may be direct targets of SlMYB12 regulation.
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