ArticlePlant physiology2016
Maize Homologs of CCoAOMT and HCT, Two Key Enzymes in Lignin Biosynthesis, Form Complexes with the NLR Rp1 Protein to Modulate the Defense Response.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- The BTB/POZ-MATH Protein ZmBPM1 Interacts With Autophagy-related Protein ZmATG6 and Modulates the NLR Protein Rp1-D21-Mediated Defense Response in Maize.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Integrated Transcriptomic and Metabolic Analyses Reveal Key Defense Pathways AgainstPlants (Basel, Switzerland) · 2026Article
- The Zma-miRNA319-ZmMYB74 Module Regulates Maize Resistance to Stalk Rot Disease by Modulating Lignin Deposition.Plant biotechnology journal · 2026Article
- Integrating GWAS and gene expression to decipher genetic components of pericarp thickness and soluble sugars in sweet corn.BMC plant biology · 2026Article
- Integrated analysis of transcriptome and metabolome reveals the mechanism of lignin biosynthesis in fruit abscission of Chinese bayberry (Myrica rubra).BMC plant biology · 2025Article
- Decades' progress and prospects on maize functional genomics and molecular breeding.Science China. Life sciences · 2025Review
- A maize mutant in the glutamate receptor-like dwarf13 is modified by cis-acting natural variation and a cornichon homolog.PLoS genetics · 2025Article
- Genome-wide association study identifies quantitative trait loci associated with resistance to Verticillium dahliae race 3 in tomato.The plant genome · 2025Article
- Sunlight-sensitive carbon dots for plant immunity priming and pathogen defence.Plant biotechnology journal · 2025Article
- Integrated metabolome and transcriptome analysis of maize roots response to different degrees of drought stress.BMC plant biology · 2025Article
- Genome-wide identification and expression analysis ofFrontiers in plant science · 2025Article
- Use of the Puccinia sorghi haustorial transcriptome to identify and characterize AvrRp1-D recognized by the maize Rp1-D resistance protein.PLoS pathogens · 2024Article
- Genome-Wide Analysis of Caffeoyl-CoA-O-methyltransferase (CCoAOMT) Family Genes and the Roles ofPlants (Basel, Switzerland) · 2024Article
- Review
- Grass lignin: biosynthesis, biological roles, and industrial applications.Frontiers in plant science · 2024Review
- Characterization and fine mapping of a maize lesion mimic mutant (Les8) with enhanced resistance to Curvularia leaf spot and southern leaf blight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Integrative transcriptome and proteome analysis reveals maize responses to Fusarium verticillioides infection inside the stalks.Molecular plant pathology · 2023Article
- Special issue: Genetics of maize-microbe interactions.Molecular plant pathology · 2023Article
- The maize ZmVPS23-like protein relocates the nucleotide-binding leucine-rich repeat protein Rp1-D21 to endosomes and suppresses the defense response.The Plant cell · 2023Article
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2 authors.
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Abstract
Disease resistance (R) genes encode nucleotide binding Leu-rich-repeat (NLR) proteins that confer resistance to specific pathogens. Upon pathogen recognition they trigger a defense response that usually includes a so-called hypersensitive response (HR), a rapid localized cell death at the site of pathogen infection. Intragenic recombination between two maize (Zea mays) NLRs, Rp1-D and Rp1-dp2, resulted in the formation of a hybrid NLR, Rp1-D21, which confers an autoactive HR in the absence of pathogen infection. From a previous quantitative trait loci and genome-wide association study, we identified genes encoding two key enzymes in lignin biosynthesis, hydroxycinnamoyltransferase (HCT) and caffeoyl CoA O-methyltransferase (CCoAOMT), adjacent to the nucleotide polymorphisms that were highly associated with variation in the severity of Rp1-D21-induced HR We have previously shown that the two maize HCT homologs suppress the HR conferred by Rp1-D21 in a heterologous system, very likely through physical interaction. Here, we show, similarly, that CCoAOMT2 suppresses the HR induced by either the full-length or by the N-terminal coiled-coil domain of Rp1-D21 also likely via physical interaction and that the metabolic activity of CCoAOMT2 is unlikely to be necessary for its role in suppressing HR. We also demonstrate that CCoAOMT2, HCTs, and Rp1 proteins can form in the same complexes. A model is derived to explain the roles of CCoAOMT and HCT in Rp1-mediated defense resistance.
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