Evidence map›Paper›PMID 27206762›Full record

ArticleJournal of nephrology2017

Proton pump inhibitors and symptomatic hypomagnesemic hypoparathyroidism.

P Fatuzzo, G Portale, V Scollo, L Zanoli, Antonio Granata

Abstract readCase Reports
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In one paragraph

Article in Journal of nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

P FatuzzoDepartment of Clinical and Experimental Medicine, School of Nephrology, University of Catania, A.O.U. "Policlinico-Vittorio Emanuele", Catania, Italy.
G PortaleDepartment of Clinical and Experimental Medicine, School of Nephrology, University of Catania, A.O.U. "Policlinico-Vittorio Emanuele", Catania, Italy.
V ScolloDepartment of Clinical and Experimental Medicine, School of Nephrology, University of Catania, A.O.U. "Policlinico-Vittorio Emanuele", Catania, Italy.
L ZanoliDepartment of Clinical and Experimental Medicine, School of Nephrology, University of Catania, A.O.U. "Policlinico-Vittorio Emanuele", Catania, Italy.
Antonio GranataNephrology and Dialysis Unit, P.O. "San Giovanni di Dio", Agrigento, Italy. antonio.granata4@tin.it.
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITNuovo Ospedale San Giovanni di Dio · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypomagnesemia is a common but often overlooked problem in hospitalized patients. Unrecognized hypomagnesemia can cause serious complications. The association of hypokalemia and hypocalcemia is strongly evocative of a magnesium deficiency. Research into the causes of hypomagnesemia is imperative, as it will definitely change the approach, treatment and prognosis. We report the case of a 65-year-old man with chronic hypocalcemia and hypokalemia associated with cerebellar syndrome, a solitary seizure and cerebellar hyperintensities on magnetic resonance imaging. After the detection and treatment of hypomagnesemia with oral supplements of magnesium and the replacement of pantoprazole with ranitidine, we observed immediate relief of the symptoms. In conclusion, in clinical practice, magnesium depletion should be investigated in elderly patients with hypocalcemia treated with proton pump inhibitors for many years, in particular in the presence of neurological disorders.

Indexed as

2-PyridinylmethylsulfinylbenzimidazolesAgedBiomarkersCerebellar DiseasesDietary SupplementsDrug SubstitutionHumansHypocalcemiaHypokalemiaHypoparathyroidismMagnesiumMalePantoprazoleProton Pump InhibitorsPyrrolidonecarboxylic AcidRanitidine2-PyridinylmethylsulfinylbenzimidazolesBiomarkersMagnesiumPantoprazoleProton Pump InhibitorsPyrrolidonecarboxylic AcidRanitidineHypocalcemiaHypokalemiaHypomagnesemiaHypoparathyroidismProton pump inhibitors

Identifiers

PMID27206762
OpenAlexW2396713944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.