ReviewIndian journal of pediatrics2016
Current Concepts in the Management of Meconium Aspiration Syndrome.
Review in Indian journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- The Care of Preterm and Term Newborns with Respiratory Conditions: A Systematic Synthesis of Evidence from Low- and Middle-Income Countries.Neonatology · 2025Pooled it
- Early versus late parenteral nutrition for critically ill term and late preterm infants.The Cochrane database of systematic reviews · 2020Pooled it
- Nebulized Magnesium Sulfate for Treatment of Persistent Pulmonary Hypertension of Newborn: A Pilot Randomized Controlled Trial.Indian journal of pediatrics · 2021Trial
- Less invasive surfactant administration for meconium aspiration syndrome.BMJ paediatrics open · 2025Article
- Perinatal predictors of clinical instability at birth in late-preterm and term infants.European journal of pediatrics · 2023Article
- Clinical characteristics of meconium aspiration syndrome in neonates with different gestational ages and the risk factors for neurological injury and death: A 9-year cohort study.Frontiers in pediatrics · 2023Article
- Early versus late parenteral nutrition in term and late preterm infants: study protocol for a randomised controlled trial.BMC pediatrics · 2022Article
- Routine Tracheal Intubation and Meconium Suctioning in Non-Vigorous Neonates with Meconium-Stained Amniotic Fluid: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Review
- Pathophysiology of Perinatal Asphyxia in Humans and Animal Models.Biomedicines · 2022Review
- A retrospective cohort study of tracheal intubation for meconium suction in nonvigorous neonates.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- The clinical effects of high-frequency oscillatory ventilation in the treatment of neonatal severe meconium aspiration syndrome complicated with severe acute respiratory distress syndrome.BMC pediatrics · 2021Article
- Neonatal Respiratory Distress Secondary to Meconium Aspiration Syndrome.Children (Basel, Switzerland) · 2021Review
- "Current concepts in assisted mechanical ventilation in the neonate" - Part 2: Understanding various modes of mechanical ventilation and recommendations for individualized disease-based approach in neonates.International journal of pediatrics & adolescent medicine · 2020Review
- [Clinical features and prognosis of meconium aspiration syndrome complicated by pulmonary hemorrhage in neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019Article
- Effectiveness of high-frequency oscillatory ventilation for the treatment of neonatal meconium aspiration syndrome.Medicine · 2019Review
- Ultrasound in neonatal lung disease.Quantitative imaging in medicine and surgery · 2018Review
- Clinical features and prognosis of severe meconium aspiration syndrome with acute respiratory distress syndrome.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In developing countries, meconium aspiration syndrome (MAS) is an important cause of morbidity and mortality among neonates. The concepts of pathophysiology and management of meconium stained amniotic fluid (MSAF) and meconium aspiration syndrome have undergone tremendous change in recent years. Routine intranatal and postnatal endotracheal suctioning of meconium in vigorous infants is no longer recommended. Recent studies have challenged its role even in non-vigorous infants. Supportive therapy like oxygen supplementation, mechanical ventilation and intravenous fluids are the cornerstone in the management of meconium aspiration syndrome. Availability of surfactant, inhaled nitric oxide, high frequency ventilators and extracorporeal membrane oxygenation has made it possible to salvage more infants with meconium aspiration syndrome. In this review the authors have discussed the current concepts in the pathophysiology and management of MAS. Drugs in trials and future therapeutic targets are also discussed briefly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.