Evidence map›Paper›PMID 27206623›Full record

ArticleSleep & breathing = Schlaf & Atmung2017

Serum high-density lipoprotein correlates with serum apolipoprotein M and A5 in obstructive sleep apnea hypopnea syndrome.

Shengyu Tan, Xianling Liu, Yan Xu, Lu Luo, Shenghua Zhou, Yawen Gao

Open access · hybridAbstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. The novel indicators of moderate to severe sleep apnea: fibrinogen to albumin ratio vs. CRP to albumin ratio.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shengyu TanDepartment of Gerontology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Xianling LiuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Yan XuDepartment of Gerontology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Lu LuoDepartment of Gerontology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Shenghua ZhouDepartment of Cardiovascularology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Yawen GaoDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China. gaoyawensci@126.com.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate the correlation between serum levels of serum apolipoprotein M (ApoM), A5 (ApoA5), and high-density lipoprotein (HDL) in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and study the effects of nasal continuous positive airway pressure treatment on these serum biomarkers.

methodsThirty OSAHS patients and 15 non-OSAHS probands as control were selected for the study. Serum HDL, ApoM, and ApoA5 levels in two groups were detected; differences and association among them were analyzed. Patients with moderate and severe OSAHS underwent 3-month auto-continuous positive airway pressure treatment, and a comparative study was conducted to investigate the changes in blood lipids, serum ApoM, and ApoA5.

resultsIn comparison to the control group, the HDL, ApoM, and ApoA5 serum levels were lower (P < 0.05). HDL was positively correlated to ApoM and ApoA5 (P < 0.001), and ApoM was positively correlated to ApoA5 (r = 0.536, P < 0.001). HDL, ApoM, and ApoA5 were significantly increased in the patients of moderate and severe OSAHS after auto-continuous positive airway pressure treatment for 3 months (P < 0.05).

conclusionsThe HDL level was significantly lower in OSAHS patients. The decrease in serum ApoM and ApoA5 in OSAHS patients was correlated to the severity of OSAHS and HDL levels. Auto-continuous positive airway pressure treatment increased serum levels of ApoM, ApoA5, and HDL in OSAHS patients.

Indexed as

AdultApolipoprotein A-VApolipoproteins MBiomarkersContinuous Positive Airway PressureFemaleHumansLipoproteins, HDLMaleMiddle AgedMultivariate AnalysisPolysomnographyRetrospective StudiesRisk FactorsSignal Processing, Computer-AssistedSleep Apnea, ObstructiveAPOA5 protein, humanApolipoprotein A-VApolipoproteins MBiomarkersLipoproteins, HDLApolipoprotein A5Apolipoprotein MHigh-density lipoproteinNasal continuous positive airway pressure treatmentObstructive sleep apnea hypopnea syndrome

Identifiers

PMID27206623
PMCPMC5343088
OpenAlexW2398156684

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.