Evidence map›Paper›PMID 27206523›Full record

ArticleVirology journal2016

Graves' hyperthyroidism accompanied with acute hepatitis B virus infection: an extrahepatic manifestation?

Wei Cui, Baocheng Deng, Wen Wang, Pei Liu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Virology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A Case of Graves' Disease Accompanied with Acute Hepatitis A Virus Infection.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wei CuiDepartment of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang, China.
Baocheng DengDepartment of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang, China.
Wen WangDepartment of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang, China.
Pei LiuDepartment of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang, China. weicuisy@163.com.
China Medical University · CNFirst Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough hepatitis B virus (HBV) primarily affects hepatocytes, it has also been shown to cause complications in the skin, joints, muscles, and kidneys. Thyroid dysfunction is uncommon in cases of acute HBV infection. CASE PRESENTATION: In this report, we describe a case of a 46-year-old woman with incipient acute hepatitis B virus (HBV) infection who presented clinically with Graves' hyperthyroidism. She showed typical symptoms of hyperthyroidism, and laboratory tests revealed high levels of HBV DNA and alanine transaminase (ALT). The patient was not administered with antithyroid medicine or radioiodine, but she was given antiviral therapy and symptomatic treatment with propranolol. Follow-up studies showed that as the HBV DNA levels decreased, the thyroid function recovered.

conclusionGraves' disease maybe an extrahepatic manifestation of acute HBV infection. Antiviral therapy is likely to be beneficial for this condition as without severe thyrotoxicosis.

Indexed as

Antiviral AgentsFemaleGraves DiseaseHepatitis BHumansMiddle AgedTreatment OutcomeAntiviral AgentsAntiviralExtrahepatic manifestationGraves’ hyperthyroidismHBV infection

Identifiers

PMID27206523
PMCPMC4874021
OpenAlexW2394539415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.