Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2016
Outpatient treatment of acute poisoning by substances of abuse: a prospective observational cohort study.
Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Acute recreational drug and ethanol poisoning among adolescents: An observational study from Oslo, Norway 2014-2023.Toxicology reports · 2025Article
- The INTOXICATE study: methodology and preliminary results of a prospective observational study.Critical care (London, England) · 2024Observational
- Indian Society of Critical Care Medicine Position Statement: Approach to a Patient with Poisoning in the Emergency Room and Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Observational
- Self-discharge during treatment for acute recreational drug toxicity: an observational study from emergency departments in seven European countries.International journal of emergency medicine · 2023Article
- Poisoning with central stimulant drugs: an observational study from Oslo, Norway.International journal of emergency medicine · 2022Article
- Unspecified opioids among opioid overdoses in Oslo, Norway.BMC research notes · 2022Article
- Treating patients with opioid overdose at a primary care emergency outpatient clinic: a cost-minimization analysis.Cost effectiveness and resource allocation : C/E · 2021Article
- Acute poisoning related to the recreational use of prescription drugs: an observational study from Oslo, Norway.BMC emergency medicine · 2019Observational
- Mortality and repeated poisoning after self-discharge during treatment for acute poisoning by substances of abuse: a prospective observational cohort study.BMC emergency medicine · 2019Observational
- Factors associated with rapidly repeated acute poisoning by substances of abuse: a prospective observational cohort study.BMC research notes · 2018Observational
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProcedures for the clinical assessment of acute poisoning by substances of abuse should identify patients in need of hospital admission and avoid hazardous discharges, while keeping the observation time short. We assess the safety of a systematic procedure developed at the Oslo Accident and Emergency Outpatient Clinic (OAEOC).
methodsAll patients 12 years and older treated for acute poisoning by substances of abuse at the OAEOC were included consecutively from October 2011 to September 2012. Data were collected on pre-set registration forms. Information on re-presentations to health services nation-wide during the first week following discharge was retrieved from the Norwegian Patient Register and from local electronic medical records. Information on fatalities was obtained from the Norwegian Cause of Death Registry.
resultsThere were 2343 cases of acute poisoning by substances of abuse. The main toxic agent was ethanol in 1291 (55 %) cases, opioids in 539 (23 %), benzodiazepines in 194 (8 %), central stimulants in 132 (6 %), and gamma-hydroxybutyrate (GHB) in 105 (4 %). Median observation time was four hours. The patient was hospitalised in 391 (17 %) cases. Two patients died during the first week following discharge, both from a new opioid poisoning. Among 1952 discharges, 375 (19 %) patients re-presented at the OAEOC or a hospital within a week; 13 (0.7 %) with a diagnosis missed at the index episode, 169 (9 %) with a new poisoning, 31 (2 %) for follow-up of concomitant conditions diagnosed at index, and 162 (8 %) for unrelated events. Among the patients with missed diagnoses, five needed further treatment for the same poisoning episode, two were admitted with psychosis, one had hemorrhagic gastritis, another had fractures in need of surgery and four had minor injuries.
conclusionThe procedure in use at the OAEOC can be considered safe and could be implemented elsewhere. The high re-presentation rate calls for better follow-up.
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