Evidence map›Paper›PMID 27203443›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2016

Strand and Cell Type-specific Function of microRNA-126 in Angiogenesis.

Qinbo Zhou, Chastain Anderson, Jakub Hanus, Fangkun Zhao, Jing Ma, Akihiko Yoshimura, Shusheng Wang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Qinbo ZhouDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, USA.
Chastain AndersonDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, USA.
Jakub HanusDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, USA.
Fangkun ZhaoDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, USA.
Jing MaDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, USA.
Akihiko YoshimuraDepartment of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Shusheng WangDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, USA.
Tulane University · USKeio University · JP

Funding

Regulation of Ocular Angiogenesis by microRNAsR01EY021862 · NEI · UT SOUTHWESTERN MEDICAL CENTER · PI WANG, SHUSHENG · 2011 to 2021
$2.8M
Role of long noncoding RNAs in human ocular angiogenesisR01EY026069 · NEI · TULANE UNIVERSITY OF LOUISIANA · PI WANG, SHUSHENG · 2016 to 2020
$1.9M
NEI NIH HHS R01 EY021862NEI NIH HHS R01 EY026069
6 · The paper itself

Abstract

microRNAs or miRs have been shown to be pivotal modulators of vascular development. The strand and cell type-specific function of miR-126 in angiogenesis, especially pathological angiogenesis, remains poorly defined. We characterized the retinal vascular phenotype of miR-126

Indexed as

Neovascularization, PhysiologicAdaptor Proteins, Signal TransducingAnimalsCell ProliferationCoculture TechniquesDisease Models, AnimalEyeFibroblastsGene Expression RegulationGene Knockout TechniquesHumansHuman Umbilical Vein Endothelial CellsIntracellular Signaling Peptides and ProteinsMacular DegenerationMembrane ProteinsMiceAdaptor Proteins, Signal TransducingIntracellular Signaling Peptides and ProteinsMembrane ProteinsMicroRNAsMIRN126 microRNA, humanSPRED1 protein, humanVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID27203443
PMCPMC5112035
OpenAlexW2399798984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.