ArticleInternational journal of reproductive biomedicine2016
Effects of aqueous extract from Asparagus officinalis L. roots on hypothalamic-pituitary-gonadal axis hormone levels and the number of ovarian follicles in adult rats.
Article in International journal of reproductive biomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Harnessing phytochemicals for engineering health solutions.Human genomics · 2026Review
- Protective effects of corn silk andToxicology research · 2025Article
- Effects of Integrated Extracts ofAntioxidants (Basel, Switzerland) · 2025Article
- Article
- A Review of the Pro-Health Activity ofFoods (Basel, Switzerland) · 2024Review
- Literature analysis on asparagus roots and review of its functional characterizations.Frontiers in nutrition · 2022Review
- Long Term Oral Administration of Oregano Essence Effectively Relieves Polycystic Ovarian Rats through Endocrine and Inflammatory Balance.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells.Scientific reports · 2021Article
- Therapeutic Promises of Medicinal Plants in Bangladesh and Their Bioactive Compounds against Ulcers and Inflammatory Diseases.Plants (Basel, Switzerland) · 2021Review
- Green and White AsparagusMetabolites · 2019Review
- Traditional Persian Medicine and management of metabolic dysfunction in polycystic ovary syndrome.Journal of traditional and complementary medicine · 2018Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsparagus is a plant with high nutritional, pharmaceutical, and industrial values.
objectiveThe present study aimed to evaluate the effect of aqueous extract of asparagus roots on the hypothalamic-pituitary-gonadal axis hormones and oogenesis in female rats. MATERIALS AND
methodsIn this experimental study, 40 adult female Wistar rats were divided into five groups, which consist 8 rats. Groups included control, sham and three experimental groups receiving different doses (100, 200, 400 mg/kg/bw) of aqueous extract of asparagus roots. All dosages were administered orally for 28 days. Blood samples were taken from rats to evaluate serum levels of Gonadotropin releasing hormone (GnRH), follicular stimulating hormone (FSH), Luteinal hormone (LH), estrogen, and progesterone hormones. The ovaries were removed, weighted, sectioned, and studied by light microscope.
resultsDose-dependent aqueous extract of asparagus roots significantly increased serum levels of GnRH, FSH, LH, estrogen, and progestin hormones compared to control and sham groups. Increase in number of ovarian follicles and corpus luteum in groups treated with asparagus root extract was also observed (p<0.05).
conclusionAsparagus roots extract stimulates secretion of hypothalamic- pituitary- gonadal axis hormones. This also positively affects oogenesis in female rats.
Indexed as
Identifiers
27200420PMC4869160W2294437398What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.