Evidence map›Paper›PMID 27200418›Full record

ArticleTomography (Ann Arbor, Mich.)2016

The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge.

Wei Huang, Yiyi Chen, Andriy Fedorov, Xia Li, Guido H Jajamovich, Dariya I Malyarenko, Madhava P Aryal, Peter S LaViolette, Matthew J Oborski, Finbarr O'Sullivan and 18 more

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 9 institutions in 2 countries.

Wei HuangOregon Health and Science University, Portland, OR.
Yiyi ChenOregon Health and Science University, Portland, OR.
Andriy FedorovBrigham and Women's Hospital and Harvard Medical School, Boston, MA.
Xia LiGeneral ElectricGlobal Research, Niskayuna, NY.
Guido H JajamovichIcahn School ofMedicine at Mount Sinai, New York, NY.
Dariya I MalyarenkoUniversity of Michigan, Ann Arbor, MI.
Madhava P AryalUniversity of Michigan, Ann Arbor, MI.
Peter S LaVioletteMedical College of Wisconsin, Milwaukee, WI.
Matthew J OborskiUniversity of Pittsburgh,Pittsburgh, PA.
Finbarr O'SullivanUniversity College, Cork, Ireland.
Richard G AbramsonVanderbilt University, Nashville, TN.
Kourosh Jafari-KhouzaniMassachusettsGeneral Hospital and Harvard Medical School, Boston, MA.
Aneela AfzalOregon Health and Science University, Portland, OR.
Alina TudoricaOregon Health and Science University, Portland, OR.
Brendan MoloneyOregon Health and Science University, Portland, OR.
Sandeep N GuptaGeneral ElectricGlobal Research, Niskayuna, NY.
Cecilia BesaIcahn School ofMedicine at Mount Sinai, New York, NY.
Jayashree Kalpathy-CramerMassachusettsGeneral Hospital and Harvard Medical School, Boston, MA.
James M MountzUniversity of Pittsburgh,Pittsburgh, PA.
Charles M LaymonUniversity of Pittsburgh,Pittsburgh, PA.
Mark MuziUniversity of Washington, Seattle, WA.
Kathleen SchmaindaMedical College of Wisconsin, Milwaukee, WI.
Yue CaoUniversity of Michigan, Ann Arbor, MI.
Thomas L ChenevertUniversity of Michigan, Ann Arbor, MI.
Bachir TaouliIcahn School ofMedicine at Mount Sinai, New York, NY.
Thomas E YankeelovVanderbilt University, Nashville, TN.
Fiona FennessyBrigham and Women's Hospital and Harvard Medical School, Boston, MA.
Xin LiOregon Health and Science University, Portland, OR.
General Electric (United States) · USOregon Health & Science University · USUniversity of Pittsburgh · USUniversity of Michigan · USBrigham and Women's Hospital · USHarvard University · USMedical College of Wisconsin · USUniversity of Washington · USVanderbilt University · US

Funding

QUANTITATION OF HUMAN BRAIN TUMOR THERAPY RESPONSE BY MRP01CA085878 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHNSON, TIMOTHY D · 2001 to 2017
$31.9M
Advanced PET/CT Imaging for Improving Clinical TrialsU01CA148131 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E., LINDEN, HANNAH M · 2010 to 2019
$6.0M
Quantitative (Perfusion and Diffusion) MRI Biomarkers to Measure Glioma ResponseU01CA176110 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI SCHMAINDA, KATHLEEN MARIE · 2014 to 2023
$4.9M
Quantitative MRI for Predicting Response of Breast Cancer to Neoadjuvant TherapyU01CA142565 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KARCZMAR, GREGORY S., NANDA, RITA · 2010 to 2019
$4.5M
Quantitative DW-MRI for Early Breast Cancer Treatment Response AssessmentU01CA166104 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHENEVERT, THOMAS L, GALBAN, CRAIG J · 2012 to 2019
$4.1M
Informatics Tools for Optimized Imaging Biomarkers for Cancer Research&DiscoveryU24CA180927 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI KALPATHY-CRAMER, JAYASHREE, ROSEN, BRUCE R · 2014 to 2018
$3.4M
Quantitative MRI of Glioblastoma ResponseU01CA154601 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI KALPATHY-CRAMER, JAYASHREE · 2011 to 2016
$3.4M
Shutter-Speed Model DCE-MRI for Assessment of Response to Cancer TherapyU01CA154602 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HUANG, WEI, RYAN, CHRISTOPHER WALTER · 2011 to 2015
$2.9M
Evaluation of HCC Response to Systemic Therapy with Quantitative MRIU01CA172320 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI TAOULI, BACHIR · 2013 to 2017
$2.6M
Quantitative Biomarker Imaging for Early Therapy Response Assessment in CancerU01CA140230 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOUNTZ, JAMES M. · 2009 to 2013
$2.1M
Quantitative MRI models of HN Cancers for Physiological Adaption of RTU01CA183848 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CAO, YUE · 2014 to 2019
$2.0M
Quantitiative MRI of prostate cancer as a biomarker and guide for treatmentU01CA151261 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FENNESSY, FIONA · 2010 to 2014
$1.8M
NCI NIH HHS P01 CA085878NCI NIH HHS U01 CA140230NCI NIH HHS U01 CA142565NCI NIH HHS U01 CA148131NCI NIH HHS U01 CA151261NCI NIH HHS U01 CA154601NCI NIH HHS U01 CA154602NCI NIH HHS U01 CA166104NCI NIH HHS U01 CA172320NCI NIH HHS U01 CA176110NCI NIH HHS U01 CA183848NCI NIH HHS U24 CA180927
6 · The paper itself

Abstract

Dynamic contrast-enhanced MRI (DCE-MRI) has been widely used in tumor detection and therapy response evaluation. Pharmacokinetic analysis of DCE-MRI time-course data allows estimation of quantitative imaging biomarkers such as K

Identifiers

PMID27200418
PMCPMC4869732
OpenAlexW4212948410

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.