ArticleFrontiers in microbiology2016
Transcriptomic Analysis Reveals Adaptive Responses of an Enterobacteriaceae Strain LSJC7 to Arsenic Exposure.
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- As(III) Exposure Induces a Zinc Scarcity Response and Restricts Iron Uptake in High-Level Arsenic-Resistant Paenibacillus taichungensis Strain NC1.Applied and environmental microbiology · 2022Article
- Transcriptomic Analysis of the Dual Response of Rhodococcus aetherivorans BCP1 to Inorganic Arsenic Oxyanions.Applied and environmental microbiology · 2022Article
- Transcriptomics and Functional Analysis of Copper Stress Response in the Sulfate-Reducing BacteriumInternational journal of molecular sciences · 2022Article
- Comparative transcriptomics reveal different genetic adaptations of biofilm formation inFrontiers in microbiology · 2022Article
- Transcriptome Approach Reveals the Response Mechanism ofFrontiers in plant science · 2022Article
- Proteomics and transcriptomic analysis ofCurrent research in microbial sciences · 2021Article
- Discerning the role of a functional arsenic-resistance cassette in the evolution and adaptation of a rice pathogen.Microbial genomics · 2021Article
- Arsenate-Induced Changes in Bacterial Metabolite and Lipid Pools during Phosphate Stress.Applied and environmental microbiology · 2021Article
- Transcriptomic Response Analysis ofFrontiers in microbiology · 2021Article
- Cellular response of Brevibacterium casei #NIOSBA88 to arsenic and chromium-a proteomic approach.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Root-Bacteria Associations Boost Rhizosheath Formation in Moderately Dry Soil through Ethylene Responses.Plant physiology · 2020Article
- Moderate water stress in rice induces rhizosheath formation associated with abscisic acid and auxin responses.Journal of experimental botany · 2020Article
- Arsenic Response of Three AltiplanicFrontiers in microbiology · 2019Article
- Transcriptomic Analysis of TwoFrontiers in microbiology · 2019Article
- Differential protein expression in a marine-derived3 Biotech · 2018Article
- Article
- Linking Genes to Microbial Biogeochemical Cycling: Lessons from Arsenic.Environmental science & technology · 2017Article
- Transcriptomic analysis of the response of Pseudomonas fluorescens to epigallocatechin gallate by RNA-seq.PloS one · 2017Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arsenic (As) resistance determinant ars operon is present in many bacteria and has been demonstrated to enhance As(V) resistance of bacteria. However, whole molecular mechanism adaptations of bacteria in response to As(V) stress remain largely unknown. In this study, transcriptional profiles of Enterobacteriaceae strain LSJC7 responding to As(V) stress were analyzed using RNA-seq and qRT-PCR. As expected, genes involved in As(V) uptake were down-regulated, those involved in As(V) reduction and As(III) efflux were up-regulated, which avoided cellular As accumulation. Reactive oxygen species and nitric oxide (NO) were induced, which caused cellular damages including DNA, protein, and Fe-S cluster damage in LSJC7. The expression of specific genes encoding transcriptional regulators, such as nsrR and soxRS were also induced. NsrR and SoxRS modulated many critical metabolic activities in As(V) stressed LSJC7 cells, including reactive species scavenging and repairing damaged DNA, proteins, and Fe-S clusters. Therefore, besides As uptake, reduction, and efflux; oxidative stress defense and damage repair were the main cellular adaptive responses of LSJC7 to As(V) stress.
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