ArticleFrontiers in microbiology2016
Experimental Evolution on a Wild Mammal Species Results in Modifications of Gut Microbial Communities.
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Selection and transmission of the gut microbiome alone can shift mammalian behavior.Nature communications · 2025Article
- Beyond the laboratory: the bank vole (Clethrionomys glareolus) as a novel model organism in biological research.Frontiers in zoology · 2025Review
- Gut Microecology of Four Sympatric Desert Rodents Varies by Diet.Ecology and evolution · 2025Article
- Experimental evolution of a mammalian holobiont: bank voles selected for herbivorous capability evolved distinct and robust gut bacterial communities.ISME communications · 2025Article
- Article
- Host specificity of the gut microbiome.Nature reviews. Microbiology · 2021Review
- Evolution of pathogen tolerance and emerging infections: A missing experimental paradigm.eLife · 2021Review
- Comparative analysis of oral-gut microbiota between captive and wild long-tailed macaque in Thailand.Scientific reports · 2021Article
- Early-life effects of juvenile Western diet and exercise on adult gut microbiome composition in mice.The Journal of experimental biology · 2021Article
- Optimal integration between host physiology and functions of the gut microbiome.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Captivity affects diversity, abundance, and functional pathways of gut microbiota in the northern grass lizard Takydromus septentrionalis.MicrobiologyOpen · 2020Article
- Ecological and evolutionary mechanisms underlying patterns of phylosymbiosis in host-associated microbial communities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Experimental evolution of personality traits: open-field exploration in bank voles from a multidirectional selection experiment.Current zoology · 2019Article
- Experimental bacterial adaptation to the zebrafish gut reveals a primary role for immigration.PLoS biology · 2018Article
- Conservation Implications of Shifting Gut Microbiomes in Captive-Reared Endangered Voles Intended for Reintroduction into the Wild.Microorganisms · 2018Article
- Article
- Review
- Evolving as a holobiont.PLoS biology · 2017Review
- Experimental Evolution as an Underutilized Tool for Studying Beneficial Animal-Microbe Interactions.Frontiers in microbiology · 2016Review
- Article
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Authors and funding
5 authors.
Funding
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Abstract
Comparative studies have shown that diet, life history, and phylogeny interact to determine microbial community structure across mammalian hosts. However, these studies are often confounded by numerous factors. Selection experiments offer unique opportunities to validate conclusions and test hypotheses generated by comparative studies. We used a replicated, 15-generation selection experiment on bank voles (Myodes glareolus) that have been selected for high swim-induced aerobic metabolism, predatory behavior toward crickets, and the ability to maintain body mass on a high-fiber, herbivorous diet. We predicted that selection on host performance, mimicking adaptive radiation, would result in distinct microbial signatures. We collected foregut and cecum samples from animals that were all fed the same nutrient-rich diet and had not been subjected to any performance tests. We conducted microbial inventories of gut contents by sequencing the V4 region of the 16S rRNA gene. We found no differences in cecal microbial community structure or diversity between control lines and the aerobic or predatory lines. However, the cecal chambers of voles selected for herbivorous capability harbored distinct microbial communities that exhibited higher diversity than control lines. The foregut communities of herbivorous-selected voles were also distinct from control lines. Overall, this experiment suggests that differences in microbial communities across herbivorous mammals may be evolved, and not solely driven by current diet or other transient factors.
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