ArticleFrontiers in psychology2016
Altered Gray Matter Volume and White Matter Integrity in College Students with Mobile Phone Dependence.
Article in Frontiers in psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 10 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- The neurobiology of internet addiction: a scoping review of developmental and gender-specific mechanisms.Frontiers in psychology · 2026Pooled it
- Disruptions of white matter in adolescents with internet game disorder: evidence from seed-based d mapping.Brain imaging and behavior · 2025Pooled it
- Impact of digital addiction on youth health: A systematic review and meta-analysis.Journal of behavioral addictions · 2025Pooled it
- Associations between meeting 24h movement behavior guidelines and cognition, gray matter volume, and academic performance in children and adolescents: a systematic review.Archives of public health = Archives belges de sante publique · 2025Pooled it
- Internet addiction-induced brain structure and function alterations: a systematic review and meta-analysis of voxel-based morphometry and resting-state functional connectivity studies.Brain imaging and behavior · 2023Pooled it
- Structural and Functional Neural Correlates in Individuals with Excessive Smartphone Use: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Structural gray matter differences in Problematic Usage of the Internet: a systematic review and meta-analysis.Molecular psychiatry · 2022Pooled it
- Association between mobile phone addiction and social support among mainland Chinese teenagers: A meta-analysis.Frontiers in public health · 2022Pooled it
- Shared gray matter alterations in individuals with diverse behavioral addictions: A voxel-wise meta-analysis.Journal of behavioral addictions · 2020Pooled it
- Mobile Phone Use and Mental Health. A Review of the Research That Takes a Psychological Perspective on Exposure.International journal of environmental research and public health · 2018Pooled it
- Associations Between Problematic Internet Use, Attentional Control, and Mental Health Symptoms in Romanian Adults: A Cross-Sectional Study.Diseases (Basel, Switzerland) · 2026Article
- Signs of Problematic Internet use Affect Resting-State EEG Microstates.Brain topography · 2025Article
- A longitudinal study on the relationships between impulsivity and excessive smartphone use among patients with acquired brain injury and control participants.Frontiers in psychiatry · 2025Article
- Structural covariation between cerebellum and neocortex intrinsic structural covariation links cerebellum subregions to the cerebral cortex.Journal of neurophysiology · 2024Article
- Unravelling the Enigma: How Behavioural Addictions Alter the Developing Child Brain?Annals of neurosciences · 2023Article
- The impact of physical activity on electronic media use among chinese adolescents and urban-rural differences.BMC public health · 2023Article
- Neuroimaging the effects of smartphone (over-)use on brain function and structure-a review on the current state of MRI-based findings and a roadmap for future research.Psychoradiology · 2023Review
- Structural and Functional Neural Alterations in Internet Addiction: A Study Protocol for Systematic Review and Meta-Analysis.Psychiatry investigation · 2023Article
- A perspective of yoga on smartphone addiction: A narrative review.Journal of family medicine and primary care · 2022Review
- Functional connectivity between the parahippocampal gyrus and the middle temporal gyrus moderates the relationship between problematic mobile phone use and depressive symptoms: Evidence from a longitudinal study.Journal of behavioral addictions · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mobile phone dependence (MPD) is a behavioral addiction that has become an increasing public mental health issue. While previous research has explored some of the factors that may predict MPD, the underlying neural mechanisms of MPD have not been investigated yet. The current study aimed to explore the microstructural variations associated with MPD as measured with functional Magnetic Resonance Imaging (fMRI). Gray matter volume (GMV) and white matter (WM) integrity [four indices: fractional anisotropy (FA); mean diffusivity (MD); axial diffusivity (AD); and radial diffusivity (RD)] were calculated via voxel-based morphometry (VBM) and tract-based spatial statistics (TBSS) analysis, respectively. Sixty-eight college students (42 female) were enrolled and separated into two groups [MPD group, N = 34; control group (CG), N = 34] based on Mobile Phone Addiction Index (MPAI) scale score. Trait impulsivity was also measured using the Barratt Impulsiveness Scale (BIS-11). In light of underlying trait impulsivity, results revealed decreased GMV in the MPD group relative to controls in regions such as the right superior frontal gyrus (sFG), right inferior frontal gyrus (iFG), and bilateral thalamus (Thal). In the MPD group, GMV in the above mentioned regions was negatively correlated with scores on the MPAI. Results also showed significantly less FA and AD measures of WM integrity in the MPD group relative to controls in bilateral hippocampal cingulum bundle fibers (CgH). Additionally, in the MPD group, FA of the CgH was also negatively correlated with scores on the MPAI. These findings provide the first morphological evidence of altered brain structure with mobile phone overuse, and may help to better understand the neural mechanisms of MPD in relation to other behavioral and substance addiction disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.