ArticleFrontiers in physiology2016
Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men.
Article in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation on the Recovery Kinetics of Performance, Muscle Damage and Neuromuscular Fatigue Indicators, Following Different Protocols for Muscle Power Development
Recovery Kinetics of Muscle Performance, Muscle Damage and Neuromuscular Fatigue After Different Protocols of Power Training
Who cites it
56 citing papers in PubMed, 6 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- The Effects of Advanced Resistance Training Prescription Methods on Strength, Power, Hypertrophy, and Performance Adaptations in Healthy Adults: A Systematic Review and Bayesian Network Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Acute and Chronic Effects of Accentuated Eccentric Loading vs. Constant-Load Resistance Training: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Acute Effects of Accentuated Eccentric Loading on Mean Concentric Velocity During Resistance Training: A Systematic Review and Meta-analysis.Sports medicine - open · 2026Pooled it
- Optimal resistance training strategies for knee osteoarthritis symptom relief: a systematic review and network meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Accentuated eccentric loading in lower-body resistance training: a systematic review of acute and chronic adaptations on strength, power, and speed outcomes.Frontiers in physiology · 2025Pooled it
- Maximizing Muscle Hypertrophy: A Systematic Review of Advanced Resistance Training Techniques and Methods.International journal of environmental research and public health · 2019Pooled it
- Trial
- Effects of Eccentric-Oriented Strength Training on Return to Sport Criteria in Late-Stage Anterior Cruciate Ligament (ACL)-Reconstructed Professional Team Sport Players.Medicina (Kaunas, Lithuania) · 2023Trial
- Increased fascicle length but not patellar tendon stiffness after accentuated eccentric-load strength training in already-trained men.European journal of applied physiology · 2020Trial
- Trial
- Eccentric and Concentric Resistance Exercise Comparison for Knee Osteoarthritis.Medicine and science in sports and exercise · 2019Trial
- Effects of Caffeine Supplementation on Power Performance in a Flywheel Device: A Randomised, Double-Blind Cross-Over Study.Nutrients · 2019Trial
- Isokinetic eccentric training is more effective than constant load eccentric training for quadriceps rehabilitation following anterior cruciate ligament reconstruction: a randomized controlled trial.Brazilian journal of physical therapyTrial
- Is there a threshold for use-dependent plasticity? A study of repeated motor skill training in the human lower limbs.European journal of applied physiology · 2026Article
- Performance and hormonal responses to different training modalities in young weightlifters: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2026Article
- Cross-Education Effects After Submaximal and Supramaximal Accentuated Eccentric Loading on Lean Mass and Function in Women.Journal of functional morphology and kinesiology · 2026Article
- One, two, or three times a week? examining the optimal frequency for strength and muscle growth in accentuated eccentric exercise.European journal of applied physiology · 2025Article
- The 12 weeks of regular exercise improves sleep quality and mood states in elderly with cognitive impairment.Sleep & breathing = Schlaf & Atmung · 2025Article
- Neuromuscular adaptations to resistance training in elite versus recreational athletes.Frontiers in physiology · 2025Review
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As training experience increases it becomes more challenging to induce further neuromuscular adaptation. Consequently, strength trainers seek alternative training methods in order to further increase strength and muscle mass. One method is to utilize accentuated eccentric loading, which applies a greater external load during the eccentric phase of the lift as compared to the concentric phase. Based upon this practice, the purpose of this study was to determine the effects of 10 weeks of accentuated eccentric loading vs. traditional isoinertial resistance training in strength-trained men. Young (22 ± 3 years, 177 ± 6 cm, 76 ± 10 kg, n = 28) strength-trained men (2.6 ± 2.2 years experience) were allocated to concentric-eccentric resistance training in the form of accentuated eccentric load (eccentric load = concentric load + 40%) or traditional resistance training, while the control group continued their normal unsupervised training program. Both intervention groups performed three sets of 6-RM (session 1) and three sets of 10-RM (session 2) bilateral leg press and unilateral knee extension exercises per week. Maximum force production was measured by unilateral isometric (110° knee angle) and isokinetic (concentric and eccentric 30°.s(-1)) knee extension tests, and work capacity was measured by a knee extension repetition-to-failure test. Muscle mass was assessed using panoramic ultrasonography and dual-energy x-ray absorptiometry. Surface electromyogram amplitude normalized to maximum M-wave and the twitch interpolation technique were used to examine maximal muscle activation. After training, maximum isometric torque increased significantly more in the accentuated eccentric load group than control (18 ± 10 vs. 1 ± 5%, p < 0.01), which was accompanied by an increase in voluntary activation (3.5 ± 5%, p < 0.05). Isokinetic eccentric torque increased significantly after accentuated eccentric load training only (10 ± 9%, p < 0.05), whereas concentric torque increased equally in both the accentuated eccentric load (10 ± 9%, p < 0.01) and traditional (9 ± 6%, p < 0.01) resistance training groups; however, the increase in the accentuated eccentric load group was significantly greater (p < 0.05) than control (1 ± 7%). Knee extension repetition-to-failure improved in the accentuated eccentric load group only (28%, p < 0.05). Similar increases in muscle mass occurred in both intervention groups. In summary, accentuated eccentric load training led to greater increases in maximum force production, work capacity and muscle activation, but not muscle hypertrophy, in strength-trained individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.