Evidence map›Paper›PMID 27199739›Full record

ArticleFrontiers in aging neuroscience2016

The Biomarkers for Identifying Preclinical Alzheimer's Disease via Structural and Functional Magnetic Resonance Imaging.

Yanhong Zhou, Chuangchuang Tan, Dong Wen, Hongmin Sun, Wei Han, Yuchen Xu

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02835716 (Pre-Clinical Alzheimer's), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02835716 unknown statusnot on this map

Pre-Clinical Alzheimer's (ALZ) Diagnosis (PCD) = Optimum Outcomes (OO)

Typeobservational_patient_registrySponsorMillennium Magnetic Technologies, LLCRan2016 to 2020Enrolled150ConditionsAlzheimer DiseaseArmsroflumilast, ustekinumab
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Frontiers in global women's health · 2025
    Article
  2. Article
  3. Article
  4. A method of VR-EEG scene cognitive rehabilitation training.Health information science and systems · 2021
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanhong ZhouDepartment of Computer Science and Technology, School of Mathematics and Information Science & Technology, Hebei Normal University of Science and Technology Qinhuangdao, China.
Chuangchuang TanDepartment of Electronic Information Science and Technology, School of Sciences, Yanshan University Qinhuangdao, China.
Dong WenDepartment of Computer Science and Technology, School of Information Science and Engineering, Yanshan UniversityQinhuangdao, China; The Key Laboratory for Computer Virtual Technology and System Integration of Hebei Province, Yanshan UniversityQinhuangdao, China.
Hongmin SunDepartment of Physical Education, School of Physical Education, Yanshan University Qinhuangdao, China.
Wei HanDepartment of Computer Science and Technology, School of Information Science and Engineering, Yanshan UniversityQinhuangdao, China; The Key Laboratory for Computer Virtual Technology and System Integration of Hebei Province, Yanshan UniversityQinhuangdao, China.
Yuchen XuDepartment of Computer Science and Technology, School of Information Science and Engineering, Yanshan UniversityQinhuangdao, China; The Key Laboratory for Computer Virtual Technology and System Integration of Hebei Province, Yanshan UniversityQinhuangdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cognitive reservefunctional magnetic resonance imaginggenemild cognitive impairmentpreclinical Alzheimer's diseaseproteinstructural magnetic resonance imaging

Identifiers

PMID27199739
PMCPMC4846650

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.