Evidence map›Paper›PMID 27199734›Full record

ArticleFrontiers in aging neuroscience2016

Cognitive Reserve in Dementia: Implications for Cognitive Training.

Sara Mondini, Ileana Madella, Andrea Zangrossi, Angela Bigolin, Claudia Tomasi, Marta Michieletto, Daniele Villani, Giuseppina Di Giovanni, Daniela Mapelli

Abstract read
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In one paragraph

Article in Frontiers in aging neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  14. Environmental Enrichment Preserves Retrosplenial Parvalbumin Density and Cognitive Function in Female 5xFAD Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara MondiniDepartment of General Psychology, University of PaduaPadova, Italy; Neuromotor Rehabilitation Unit, Casa di Cura Figlie di San CamilloCremona, Italy; Human Inspired Technology Research Centre, University of PaduaPadova, Italy.
Ileana MadellaDepartment of General Psychology, University of Padua Padova, Italy.
Andrea ZangrossiDepartment of General Psychology, University of PaduaPadova, Italy; Human Inspired Technology Research Centre, University of PaduaPadova, Italy.
Angela BigolinDepartment of General Psychology, University of Padua Padova, Italy.
Claudia TomasiDepartment of General Psychology, University of PaduaPadova, Italy; Neuromotor Rehabilitation Unit, Casa di Cura Figlie di San CamilloCremona, Italy.
Marta MichielettoDepartment of General Psychology, University of Padua Padova, Italy.
Daniele VillaniNeuromotor Rehabilitation Unit, Casa di Cura Figlie di San Camillo Cremona, Italy.
Giuseppina Di GiovanniIRCCS Centro S. Giovanni di Dio Fatebenefratelli Brescia, Italy.
Daniela MapelliDepartment of General Psychology, University of PaduaPadova, Italy; Human Inspired Technology Research Centre, University of PaduaPadova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive reserve (CR) is a potential mechanism to cope with brain damage. The aim of this study was to evaluate the effect of CR on a cognitive training (CT) in a group of patients with dementia. Eighty six participants with mild to moderate dementia were identified by their level of CR quantified by the CR Index questionnaire (CRIq) and underwent a cycle of CT. A global measure of cognition mini mental state examination (MMSE) was obtained before (T0) and after (T1) the training. Multiple linear regression analyses highlighted CR as a significant factor able to predict changes in cognitive performance after the CT. In particular, patients with lower CR benefited from a CT program more than those with high CR. These data show that CR can modulate the outcome of a CT program and that it should be considered as a predictive factor of neuropsychological rehabilitation training efficacy in people with dementia.

Indexed as

Alzheimer’s diseasecognitive reservecognitive trainingdementiarehabilitation

Identifiers

PMID27199734
PMCPMC4844602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.