Evidence map›Paper›PMID 27199733›Full record

ReviewFrontiers in aging neuroscience2016

Glial Modulation by N-acylethanolamides in Brain Injury and Neurodegeneration.

María I Herrera, Rodolfo Kölliker-Frers, George Barreto, Eduardo Blanco, Francisco Capani

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in aging neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Oleoylethanolamide, Neuroinflammation, and Alcohol Abuse.Frontiers in molecular neuroscience · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

María I HerreraInstituto de Investigaciones Cardiológicas, Facultad de Medicina, Universidad de Buenos Aires - Consejo Nacional de Investigaciones Científicas y TécnicasBuenos Aires, Argentina; Centro de Investigaciones en Psicología y Psicopedagogía, Facultad de Psicología, Universidad Católica ArgentinaBuenos Aires, Argentina.
Rodolfo Kölliker-FrersInstituto de Investigaciones Cardiológicas, Facultad de Medicina, Universidad de Buenos Aires - Consejo Nacional de Investigaciones Científicas y Técnicas Buenos Aires, Argentina.
George BarretoDepartment of Nutrition and Biochemistry, Faculty of Sciences, Pontificia Universidad Javeriana Bogotá, Colombia.
Eduardo BlancoDepartament de Pedagogia i Psicologia, Facultat d'Educació, Psicologia i Treball Social, Universitat de Lleida Lleida, Spain.
Francisco CapaniInstituto de Investigaciones Cardiológicas, Facultad de Medicina, Universidad de Buenos Aires - Consejo Nacional de Investigaciones Científicas y TécnicasBuenos Aires, Argentina; Facultad de Psicología, Universidad Católica ArgentinaBuenos Aires, Argentina; Departamento de Biología, Universidad Argentina John F. KennedyBuenos Aires, Argentina; Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de ChileSantiago, Chile.
University of Buenos Aires · ARPontificia Universidad Católica Argentina · ARPontificia Universidad Javeriana · COUniversitat de Lleida · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells.

Indexed as

gliosisN-acylethanolamidesneuroinflammationneuroprotectionPPARα

Identifiers

PMID27199733
PMCPMC4844606
OpenAlexW2343605123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.