ArticleInternational journal of nanomedicine2016
Phytosynthesis of silver nanoparticles using Artemisia marschalliana Sprengel aerial part extract and assessment of their antioxidant, anticancer, and antibacterial properties.
Article in International journal of nanomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 157 citations in OpenAlex.
- Green-Synthesized Silver Nanoparticles Against Acinetobacter baumannii: A Systematic Review of Antibacterial Activity, Mechanisms of Action, Toxicity, and Antibiofilm Effects.MicrobiologyOpen · 2026Pooled it
- Green-synthesized silver nanoparticles from fresh and wasteRSC advances · 2026Article
- Green Synthesis of Silver Nanoparticles Using Artemisia vestita: Phytochemical Insights and Bioactivity Against Fish Pathogens.Chemistry & biodiversity · 2026Article
- Artificial intelligence tools for AgNP-SSB-SN and AgNP-CSS-SN biosynthesis from Synechococcus PCC 11901 and Chlorella sorokiniana MSP1 for hazardous dyes remediation.Scientific reports · 2026Article
- Metal and Metal Oxide Nanoparticles UsingPlants (Basel, Switzerland) · 2026Review
- Green synthesis of silver nanoparticles from Kedrostis nana (Lam.) Cogn. extracts and its biological activities.Frontiers in chemistry · 2026Article
- Antimalarial potential of Matricaria chamomilla-derived MgO nanoparticles against Plasmodium falciparum strains: an experimental study.BMC complementary medicine and therapies · 2025Article
- Bioactive Molecules of MicroalgaeBioinorganic chemistry and applications · 2025Article
- An Outlook on Platinum-Based Active Ingredients for Dermatologic and Skincare Applications.Nanomaterials (Basel, Switzerland) · 2024Review
- Exploring the Frontier of Biopolymer-Assisted Drug Delivery: Advancements, Clinical Applications, and Future Perspectives in Cancer Nanomedicine.Drug design, development and therapy · 2024Review
- Artemisia carvifolia Buch silver nanoparticles downregulate the Rap2A gene in liver cancer.Scientific reports · 2023Article
- Metal nanoparticles as a potential technique for the diagnosis and treatment of gastrointestinal cancer: a comprehensive review.Cancer cell international · 2023Review
- Advancement in Biopolymer Assisted Cancer Theranostics.ACS applied bio materials · 2023Review
- Biogenic Silver Nanoparticles for Targeted Cancer Therapy and Enhancing Photodynamic Therapy.Cells · 2023Review
- Green, facile and fast synthesis of silver nanoparticles by using solution plasma techniques and their antibacterial and anticancer activities.RSC advances · 2023Article
- Anti-proliferative activity of Artemisia marschalliana on cancerous cell lines.BMC complementary medicine and therapies · 2023Article
- Biogenic Synthesis, Characterization, and In Vitro Biological Evaluation of Silver Nanoparticles UsingPlants (Basel, Switzerland) · 2023Article
- Current Trends and Prospects for Application of Green Synthesized Metal Nanoparticles in Cancer and COVID-19 Therapies.Viruses · 2023Review
- Green Synthesis of Bioinspired Nanoparticles Mediated from Plant Extracts ofAntibiotics (Basel, Switzerland) · 2023Review
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Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rapid phytosynthesis of silver nanoparticles (AgNPs) using an extract from the aerial parts of Artemisia marschalliana Sprengel was investigated in this study. The synthesized AgNPs using A. marschalliana extract was analyzed by UV-visible spectroscopy, X-ray diffraction, and Fourier transform infrared spectroscopy and further characterized by transmission electron microscopy, scanning electron microscopy, zeta potential, and energy-dispersive spectroscopy. Characteristic absorption bands of AgNPs were found near 430 nm in the UV-vis spectrum. Energy-dispersive spectroscopy analysis of AgNPs in the energy range 2-4 keV confirmed the silver signal due to surface plasmon resonance. Scanning electron microscopy and transmission electron microscopy results revealed that the AgNPs were mostly spherical with an average size ranging from 5 nm to 50 nm. The zeta potential value of -31 mV confirmed the stability of the AgNPs. AgNPs produced using the aqueous A. marschalliana extract might serve as a potent in vitro antioxidant, as revealed by 2,2-diphenyl-1-picryl hydrazyl assay. The present study demonstrates the anticancer properties of phytosynthesized AgNPs against human gastric carcinoma AGS cells. AgNPs exerted a dose-dependent inhibitory effect on the viability of cells. Real-time polymerase chain reaction was used for the investigation of Bax and Bcl-2 gene expression in cancer and normal cell lines. Our findings show that the mRNA levels of pro-apoptotic Bax gene expression were significantly upregulated, while the expression of anti-apoptotic Bcl-2 was declined in cells treated with AgNPs compared to normal cells. In addition, flow cytometric analysis showed that the number of early and late apoptotic AGS cells was significantly enhanced following treatment with AgNPs as compared to untreated cells. In addition, the AgNPs showed strong antibacterial properties against tested pathogenic bacteria such as Staphylococcus aureus, Bacillus cereus, Acinetobacter baumannii, and Pseudomonas aeruginosa. Based on the obtained data, we suggest that phytosynthesized AgNPs are good alternatives in the treatment of diseases because of the presence of bioactive agents.
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