Evidence map›Paper›PMID 27199475›Full record

Trial reportJournal of the Pediatric Infectious Diseases Society2016

Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma.

Jeremy D Keenan, Ida Sahlu, Lesley McGee, Vicky Cevallos, Jorge E Vidal, Sopio Chochua, Paulina Hawkins, Teshome Gebre, Zerihun Tadesse, Paul M Emerson and 3 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the Pediatric Infectious Diseases Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Antibiotics for trachoma.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Serotype Profile of Nasopharyngeal Isolates ofThe American journal of tropical medicine and hygiene · 2020
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jeremy D KeenanFrancis I Proctor Foundation, University of California, San Francisco Department of Ophthalmology, University of California, San Francisco.
Ida SahluHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Lesley McGeeRespiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Vicky CevallosFrancis I Proctor Foundation, University of California, San Francisco.
Jorge E VidalHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Sopio ChochuaHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Paulina HawkinsHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Teshome GebreThe Carter Center, Addis Ababa, Ethiopia.
Zerihun TadesseThe Carter Center, Addis Ababa, Ethiopia.
Paul M EmersonThe Carter Center, Atlanta, Georgia.
Bruce D GaynorFrancis I Proctor Foundation, University of California, San Francisco Department of Ophthalmology, University of California, San Francisco.
Thomas M LietmanFrancis I Proctor Foundation, University of California, San Francisco Department of Ophthalmology, University of California, San Francisco.
Keith P KlugmanHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.

Funding

CTSA: K12 COMPONENTKL2RR024130 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$19.3M
TRAINING IN DEMOGRAPHYT32HD007338 · NICHD · BROWN UNIVERSITY · PI ANDREW D. FOSTER · 1987 to 2026
$7.0M
TANA IIU10EY016214 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIETMAN, THOMAS M · 2004 to 2013
$4.4M
Optimal trachoma control after mass antibiotic distributionsK23EY019071 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KEENAN, JEREMY DAVID · 2008 to 2012
$982k
NCRR NIH HHS KL2 RR024130NEI NIH HHS K23 EY019071NEI NIH HHS U10 EY016214NICHD NIH HHS T32 HD007338
6 · The paper itself

Abstract

Twenty-four Ethiopian communities were randomized to receive either (1) quarterly mass azithromycin distributions for trachoma for 1 year or (2) delayed treatment. Nasopharyngeal swabs collected from separate cross-sectional population-based samples of children were processed for Streptococcus pneumoniae Mass azithromycin did not significantly alter the pneumococcal serotype distribution, and hence it would not be expected to alter vaccine coverage.

Indexed as

Anti-Bacterial AgentsAzithromycinCarrier StateChildChild, PreschoolCross-Sectional StudiesEthiopiaHumansInfantPneumococcal InfectionsSerogroupStreptococcus pneumoniaeTrachomaAnti-Bacterial AgentsAzithromycinAfricapneumococcal vaccinesserotypeStreptococcus pneumoniae

Identifiers

PMID27199475
PMCPMC5407126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.