Evidence map›Paper›PMID 27199350›Full record

ArticleFEMS microbiology letters2016

Industrial production of acetone and butanol by fermentation-100 years later.

Michael Sauer

Abstract readHistorical Article
In one paragraph

Article in FEMS microbiology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Leveraging EngineeredACS synthetic biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Sustainable production of biofuels from the algae-derived biomass.Bioprocess and biosystems engineering · 2023
    Article
  9. Synthetic metabolism forRSC chemical biology · 2022
    Article
  10. Article
  11. Article
  12. Sporulation in solventogenic and acetogenic clostridia.Applied microbiology and biotechnology · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael SauerDepartment of Biotechnology, BOKU-VIBT University of Natural Resources and Life Sciences, Vienna, Muthgasse 18, 1190 Vienna, Austria CD-Laboratory for Biotechnology of Glycerol, Muthgasse 18, 1190 Vienna, Austria Austrian Centre of Industrial Biotechnology (ACIB GmbH), Muthgasse 11, 1190 Vienna, Austria michael.sauer@boku.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial production of acetone and butanol was one of the first large-scale industrial fermentation processes of global importance. During the first part of the 20th century, it was indeed the second largest fermentation process, superseded in importance only by the ethanol fermentation. After a rapid decline after the 1950s, acetone-butanol-ethanol (ABE) fermentation has recently gained renewed interest in the context of biorefinery approaches for the production of fuels and chemicals from renewable resources. The availability of new methods and knowledge opens many new doors for industrial microbiology, and a comprehensive view on this process is worthwhile due to the new interest. This thematic issue of FEMS Microbiology Letters, dedicated to the 100th anniversary of the first industrial exploitation of Chaim Weizmann's ABE fermentation process, covers the main aspects of old and new developments, thereby outlining a model development in biotechnology. All major aspects of industrial microbiology are exemplified by this single process. This includes new technologies, such as the latest developments in metabolic engineering, the exploitation of biodiversity and discoveries of new regulatory systems such as for microbial stress tolerance, as well as technological aspects, such as bio- and down-stream processing.

Indexed as

FermentationAcetoneBiofuelsButanolsClostridiumEthanolHistory, 20th CenturyHistory, 21st CenturyIndustrial MicrobiologyMetabolic EngineeringAcetoneBiofuelsButanolsEthanolABE fermentationBiobutanolbiofuelsbiorefineryclostridiaWeizmann process

Identifiers

PMID27199350
PMCPMC4894279

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.