Evidence map›Paper›PMID 27199211›Full record

ArticleJournal of biomedical materials research. Part A2016

Fabrication, characterization, and in vitro evaluation of silver-containing arabinoxylan foams as antimicrobial wound dressing.

Donald C Aduba, Seon-Sook An, Gretchen S Selders, Juan Wang, W Andrew Yeudall, Gary L Bowlin, Todd Kitten, Hu Yang

Abstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Donald C AdubaDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia, 23284.
Seon-Sook AnPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, Virginia, 23298.
Gretchen S SeldersDepartment of Biomedical Engineering, University of Memphis, Memphis, Tennessee, 38152.
Juan WangDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, Virginia, 23219.
W Andrew YeudallDepartment of Oral Biology, Augusta University, Augusta, Georgia, 30912.
Gary L BowlinDepartment of Biomedical Engineering, University of Memphis, Memphis, Tennessee, 38152.
Todd KittenPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, Virginia, 23298.
Hu YangDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, Virginia, 23219.

Funding

EPS8 as a Driver of the Oral Cancer Initiating Cell Phenotype.R01DE024381 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI YEUDALL, WILLIAM ANDREW · 2014 to 2017
$1.3M
Hybrid Nanoparticles for GlaucomaR01EY024072 · NEI · VIRGINIA COMMONWEALTH UNIVERSITY · PI KOMPELLA, UDAY B, YANG, HU · 2014 to 2016
$1.3M
NEI NIH HHS R01 EY024072NIDCR NIH HHS R01 DE024381
6 · The paper itself

Abstract

Arabinoxylan ferulate (AXF) foams were fabricated via enzymatic peroxidase/hydrogen peroxide crosslinking reaction followed by freeze-drying and studied as a potential wound dressing material. The AXF foam's rheological, morphological, porous, and swelling properties were examined. AXF foams were found to be a viscoelastic material that proved to be highly porous and water absorbent. AXF foams possessed low endotoxin levels and were cytocompatible with fibroblasts. Silver was successfully integrated into AXF foams and slowly released over 48 h. AXF foams impregnated with silver demonstrated efficacy inhibiting bacterial growth according to a modified Kirby-Bauer disk diffusion susceptibility test. Overall, AXF foams possess appropriate material properties and the silver-loaded AXF foams showed antimicrobial activity necessary to be a candidate material in wound dressing development. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 2456-2465, 2016.

Indexed as

BandagesAnimalsAnti-Infective AgentsBacteriaBacterial InfectionsBiocompatible MaterialsDelayed-Action PreparationsFreeze DryingHorseradish PeroxidaseHumansHydrogen PeroxideMiceNIH 3T3 CellsPorositySilverWound HealingAnti-Infective AgentsarabinoxylanBiocompatible MaterialsDelayed-Action PreparationsHorseradish PeroxidaseHydrogen PeroxideSilverXylansarabinoxylanKirby-Bauer disk diffusion susceptibility testpolysaccharidesilver dressingwound healing

Identifiers

PMID27199211
PMCPMC5108242

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.