Evidence map›Paper›PMID 27198968›Full record

ArticleScientific reports2016

Nanomolar pyrophosphate detection and nucleus staining in living cells with simple terpyridine-Zn(II) complexes.

Duobin Chao, Shitan Ni

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 61 citations in OpenAlex.

  1. Water-Soluble Peptoids with Two Different Binding Sites for Strong ATP Chelation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
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  11. An uracil-linked hydroxyflavone probe for the recognition of ATP.Beilstein journal of organic chemistry · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Duobin ChaoSchool of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin, Liaoning 124221, P. R. China.
Shitan NiSchool of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin, Liaoning 124221, P. R. China.
Dalian University · CNDalian University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Great efforts have been made to develop fluorescent probes for pyrophosphate (PPi) detection. Nucleus staining with fluorescence microscopy has been also widely investigated. But fluorescent probes for PPi detection with high sensitivity in water medium and nucleus staining with low-cost non-precious metal complexes in living cells are still challenging. Herein, we report simple terpyridine-Zn(II) complexes for selective nanomolar PPi detection over ATP and ADP in water based on aggregation induced emission (AIE) and intramolecular charge transfer (ICT). In addition, these terpyridine-Zn(II) complexes were successfully employed for nucleus staining in living cells. These results demonstrated simply obtained terpyridine-Zn(II) complexes are powerful tool for PPi detection and the development of PPi-related studies.

Indexed as

Adenosine DiphosphateAdenosine TriphosphateCell NucleusCoordination ComplexesDiphosphatesFluorescent DyesHeLa CellsHumansOrganometallic CompoundsSpectrometry, FluorescenceWaterZincAdenosine DiphosphateAdenosine TriphosphateCoordination ComplexesDiphosphatesdiphosphoric acidFluorescent DyesOrganometallic CompoundsWaterZinc

Identifiers

PMID27198968
PMCPMC4873787
OpenAlexW2403120154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.