Evidence map›Paper›PMID 27198557›Full record

ArticleAIDS and behavior2017

Alcohol Interactive Toxicity Beliefs and ART Non-adherence Among HIV-Infected Current Drinkers in Mbarara, Uganda.

Robin Fatch, Nneka I Emenyonu, Winnie Muyindike, Allen Kekibiina, Sarah Woolf-King, Judith A Hahn

Abstract read
In one paragraph

Article in AIDS and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. 'We have goals but [it is difficult]'. Barriers to antiretroviral therapy adherence among women using alcohol and other drugs living with HIV in South Africa.Health expectations : an international journal of public participation in health care and health policy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robin FatchDepartment of Medicine, University of California San Francisco, Box 1224, 550 16th Street, San Francisco, CA, 94158, USA. robin.fatch@ucsf.edu.
Nneka I EmenyonuDepartment of Medicine, University of California San Francisco, Box 1224, 550 16th Street, San Francisco, CA, 94158, USA.
Winnie MuyindikeFaculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Allen KekibiinaFaculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Sarah Woolf-KingDepartment of Medicine, University of California San Francisco, Box 1224, 550 16th Street, San Francisco, CA, 94158, USA.
Judith A HahnDepartment of Medicine, University of California San Francisco, Box 1224, 550 16th Street, San Francisco, CA, 94158, USA.

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
URBAN ARCH (3/5) Uganda Cohort TB preventive therapy for HIV-infected alcohol users in Uganda: an evaluation of safety tolerability and adherenceU01AA020776 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2011 to 2021
$4.7M
Changes in Alcohol Consumption in HIV Positives in UgandaR01AA018631 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2010 to 2013
$2.0M
Training in Research Program on Alcohol Use by Persons with our at Risk for HIVK24AA022586 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2013 to 2023
$1.8M
Alcohol Use and High Risk Behavior Among HIV-Positive MenK01AA021671 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOOLF-KING, SARAH E · 2013 to 2017
$865k
NIAAA NIH HHS K01 AA021671NIAAA NIH HHS K24 AA022586NIAAA NIH HHS R01 AA018631NIAAA NIH HHS U01 AA020776NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

Interactive toxicity beliefs regarding mixing alcohol and antiretroviral therapy (ART) may influence ART adherence. HIV-infected patients in Uganda completed quarterly visits for 1 year, or one visit at 6 months, depending on study randomization. Past month ART non-adherence was less than daily or <100 % on a visual analog scale. Participants were asked if people who take alcohol should stop taking their medications (belief) and whether they occasionally stopped taking their medications in anticipation of drinking (behavior). Visits with self-reported alcohol use and ART use for ≥30 days were included. We used logistic regression to examine correlates of the interactive toxicity belief and behavior, and to determine associations with ART non-adherence. 134 participants contributed 258 study visits. The toxicity belief was endorsed at 24 %, the behavior at 15 %, and any non-adherence at 35 % of visits. In multivariable analysis, the odds of non-adherence were higher for those endorsing the toxicity behavior [adjusted odds ratio (AOR) 2.06; 95 % confidence interval (CI) 0.97-4.36] but not the toxicity belief (AOR 0.63; 95 % CI 0.32-1.26). Clear messaging about maintaining adherence, even if drinking, could benefit patients.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultAlcohol DrinkingAnti-HIV AgentsDrug InteractionsFemaleHIV InfectionsHumansMaleMedication AdherenceSelf ReportUgandaYoung AdultAnti-HIV AgentsAdherenceAfricaAlcoholARTInteractive toxicity beliefs

Identifiers

PMID27198557
PMCPMC5116271

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.