Evidence map›Paper›PMID 27198046›Full record

SynthesisPublic health nutrition2016

The effect of zinc supplementation on body composition and hormone levels related to adiposity among children: a systematic review.

Inong R Gunanti, Abdullah Al-Mamun, Lisa Schubert, Kurt Z Long

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Public health nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Trial
  6. Article
  7. Article
  8. Micronutrient status, food security, anaemia,Frontiers in nutrition · 2024
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Inong R Gunanti1School of Public Health, Faculty of Medicine and Biomedical Sciences,The University of Queensland,Brisbane,Queensland,Australia.
Abdullah Al-Mamun1School of Public Health, Faculty of Medicine and Biomedical Sciences,The University of Queensland,Brisbane,Queensland,Australia.
Lisa Schubert1School of Public Health, Faculty of Medicine and Biomedical Sciences,The University of Queensland,Brisbane,Queensland,Australia.
Kurt Z Long1School of Public Health, Faculty of Medicine and Biomedical Sciences,The University of Queensland,Brisbane,Queensland,Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide a comprehensive synthesis of the effects of Zn supplementation on childhood body composition and adiposity-related hormone levels.

designFive electronic databases were searched for randomized controlled trials of Zn supplementation studies published before 28 February 2015. No statistical pooling of results was carried out due to diversity in study designs.

settingCommunity- or hospital-based, from fourteen developing and developed countries. SUBJECTS: Children and adolescents aged 0 to 10 years.

resultsSeven of the fourteen studies reported an overall or subgroup effect of Zn supplementation on at least one parameter of body composition, when determined by anthropometric measurements (increased mid upper-arm circumference, triceps skinfold, subscapular skinfold and mid upper-arm muscle area, and decreased BMI). Three out of the fourteen studies reported increased mean value of total body water estimated by bio-impedance analysis and increased fat-free mass estimated by dual energy X-ray absorptiometry and by total body water. Zn supplementation was associated with increased fat-free mass among stunted children. One study found supplementation decreased leptin and insulin concentrations.

conclusionsDue to the use of anthropometry when determining body composition, a majority of the studies could not accurately address whether alterations in the fat and/or fat-free mass components of the body were responsible for the observed changes in body composition. The effect of Zn supplementation on body composition is not consistent but may modify fat-free mass among children with pre-existing growth failure.

Indexed as

AdiposityBody CompositionDietary SupplementsAnthropometryBody Mass IndexChildChild, PreschoolHumansInfantObesityPeptide HormonesRandomized Controlled Trials as TopicZincPeptide HormonesZincAdiposityAdiposity-related hormoneBody compositionChildrenZinc supplementation

Identifiers

PMID27198046
PMCPMC10270907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.