Evidence map›Paper›PMID 27197818›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Reducing the small-heart effect in pediatric gated myocardial perfusion single-photon emission computed tomography.

Hiroto Yoneyama, Kenichi Nakajima, Koichi Okuda, Shinro Matsuo, Masahisa Onoguchi, Seigo Kinuya, Lars Edenbrandt

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  5. Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
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  8. Ready, shoot, aim? Summary justice for small hearts in nuclear cardiology.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Hiroto YoneyamaDepartment of Radiological Technology, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa, 920-8641, Japan. kizu@cf6.so-net.ne.jp.
Kenichi NakajimaDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.
Koichi OkudaDepartment of Physics, Kanazawa Medical University, Kanazawa, Japan.
Shinro MatsuoDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.
Masahisa OnoguchiDepartment of Health Science, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Seigo KinuyaDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.
Lars EdenbrandtDepartment of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.
Kanazawa University Hospital · JPKanazawa Medical University · JPKanazawa University · JPUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe compared two reconstruction algorisms and two cardiac functional evaluation software programs in terms of their accuracy for estimating ejection fraction (EF) of small hearts (SH).

methodsThe study group consisted of 66 pediatric patients. Data were reconstructed using a filtered back projection (FBP) method without the resolution correction (RC) and an iterative method based on an ordered subset expectation maximization (OSEM) algorithm with the RC. EF was evaluated using two software programs of quantitative gated single-photon emission computed tomography (SPECT) (QGS) and cardioREPO. We compared the EF of gated myocardial perfusion SPECT to echocardiographic measurement (Echo).

resultsForty-eight of 66 patients had an end-systolic volume < 20 mL which was used as the criterion for being included in the SH group, and the SH effect led to an overestimation of EF. While significant differences were observed between Echo (66.9 ± 5.0%) and QGS-FBP without RC (76.9 ± 8.4%, P < .0001), QGS-OSEM with RC (76.6 ± 8.6%, P < .0001), and cardioREPO-FBP without RC (72.1 ± 10.0%, P = .0011), no significant difference was observed between Echo and cardioREPO-OSEM with RC (67.4 ± 6.1%) in SH group.

conclusionsIn pediatric gated myocardial perfusion SPECT, the SH effect can be significantly reduced when an OSEM algorithm is used with RC in combination with the specific cardioREPO algorithm.

Indexed as

AdolescentCardiac-Gated Single-Photon Emission Computer-Assisted TomographyChildFemaleHumansMaleMyocardial Perfusion ImagingPhantoms, ImagingStroke VolumeVentricular Function, LeftcardioREPOEjection fractionquantitative gated SPECTresolution correctionsmall-heart effect

Identifiers

PMID27197818
OpenAlexW2397979441

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.