Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2016
Alcohol Use and Breast Cancer Survival among Participants in the Women's Health Initiative.
Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Association between alcohol consumption and breast cancer incidence and prognosis: A systematic review and meta-analysis.Breast (Edinburgh, Scotland) · 2026Pooled it
- Alcohol consumption and breast cancer prognosis after breast cancer diagnosis: a systematic review and meta‑analysis of the Japanese Breast Cancer Society Clinical Practice Guideline, 2022 edition.Breast cancer (Tokyo, Japan) · 2023Pooled it
- Postdiagnosis dietary factors, supplement use and breast cancer prognosis: Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.International journal of cancer · 2023Pooled it
- Change in alcohol consumption and all-cause mortality among postmenopausal women diagnosed with breast cancer.Breast cancer research and treatment · 2026Article
- Tumor Characteristics and Event Free Survival in Older and Younger Women with Early Breast Cancer.Current oncology (Toronto, Ont.) · 2026Article
- Prevalence and Correlates of Post-Diagnosis Alcohol Use among Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Alcohol, Smoking, and Risks of Breast Cancer Recurrence and Mortality among Women with Luminal, Triple-Negative, and HER2-Overexpressing Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Adherence to Cancer Prevention Lifestyle Recommendations Before, During, and 2 Years After Treatment for High-risk Breast Cancer.JAMA network open · 2023Observational
- Measuring the Impact of the COVID-19 Pandemic on Health Behaviors and Health Care Utilization in Rural and Urban Patients with Cancer and Cancer Survivors.Cancer research communications · 2023Article
- Association of Cigarette Smoking and Alcohol Consumption With Subsequent Mortality Among Black Breast Cancer Survivors in New Jersey.JAMA network open · 2023Article
- Association of antidiabetic medication and statins with survival from ductal and lobular breast carcinoma in women with type 2 diabetes.Scientific reports · 2021Article
- Alcohol's Effects on Breast Cancer in Women.Alcohol research : current reviews · 2020Review
- Pre-diagnosis alcohol consumption and mortality risk among black women and white women with invasive breast cancer.BMC cancer · 2019Article
- Alcohol consumption and survival after breast cancer diagnosis in Japanese women: A prospective patient cohort study.PloS one · 2019Article
- Interactions between Alcohol Consumption and Adjuvant Hormone Therapy in Relation to Breast Cancer-Free Survival.Journal of breast cancer · 2018Article
- Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk.Current breast cancer reports · 2018Article
- Article
- Effects of Alcohol Consumption Frequency on Health Index in Korean Women.Iranian journal of public health · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAlcohol increases the risk of breast cancer even at moderate levels of intake. However, the relationship between alcohol consumption and mortality among breast cancer patients is less clear.
methodsThis study included women from the Women's Health Initiative observational study and randomized trial diagnosed with breast cancer (n = 7,835). Cox proportional hazards regression was used to estimate adjusted HRs and 95% confidence intervals (CI) for overall and breast cancer-specific (BCS) mortality associated with drinking alcohol before or after a breast cancer diagnosis. We also assessed whether changes in drinking habits after diagnosis are related to mortality.
resultsWomen who were consuming alcohol prior to their breast cancer diagnosis had a nonstatistically significant 24% (95% CI, 0.56-1.04) reduced risk of BCS mortality and a 26% (95% CI, 0.61-0.89) reduced risk of all-cause mortality. Some variation was observed by estrogen receptor (ER) status as alcohol consumption was associated with a 49% (95% CI, 0.31-0.83) reduced risk of BCS mortality among ER(-) patients with no change in risk observed among ER(+) patients (HR = 0.97; 95% CI, 0.31-1.54), though the difference between these risks was not statistically significant (P for interaction = 0.39). Postdiagnosis alcohol consumption, and change in consumption patterns after diagnosis, did not appear to be associated with all-cause or BCS mortality.
conclusionIn this large study, consumption of alcohol before or after breast cancer diagnosis did not increase risks of overall or cause-specific mortality. IMPACT: Coupled with existing evidence, alcohol consumption is unlikely to have a substantial impact on mortality among breast cancer patients. Cancer Epidemiol Biomarkers Prev; 25(8); 1268-73. ©2016 AACR.
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