ArticleCardiovascular journal of Africa
Endothelial dysfunction and arterial stiffness in pre-eclampsia demonstrated by the EndoPAT method.
Article in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05091827 (Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsia in Utero), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsia in Utero
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Arterial stiffness after 6 weeks postdelivery in women with a history of hypertensive disorders of pregnancy: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- L-Arginine and B vitamins improve endothelial function in subjects with mild to moderate blood pressure elevation.European journal of nutrition · 2018Trial
- Cumulative Low-Level Viraemia Is Not Associated with Endothelial Function in Black African Adults With HIV.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- A randomized, 12-month, parallel-group trial testing the effects of a cognitive behavioral healthy lifestyle intervention as an adjunct to standard trauma therapy among adults with PTSD: the I-CHAT study protocol.Frontiers in psychology · 2025Article
- Correlation of peripheral blood pressure with central blood pressure and estimation of central blood pressure thresholds for diagnosis of hypertension during pregnancy.Frontiers in medicine · 2025Article
- Differences between macrovascular and microvascular functions in pregnant women with chronic hypertension or preeclampsia: new insights into maternal vascular health.Frontiers in physiology · 2025Article
- Investigating the relationship between early cardiovascular disease markers and loneliness in young adults.Scientific reports · 2024Article
- Pathophysiology of Pre-Eclampsia-Two Theories of the Development of the Disease.International journal of molecular sciences · 2023Review
- Endothelial Dysfunction and Pregnant COVID-19 Patients with Thrombophilia: A Narrative Review.Biomedicines · 2023Review
- Examining changes in vascular function, arterial stiffness and systemic inflammation during hospitalization and recovery from an acute exacerbation of chronic obstructive pulmonary disease.Scientific reports · 2023Article
- Midgestation Leptin Infusion Induces Characteristics of Clinical Preeclampsia in Mice, Which Is Ablated by Endothelial Mineralocorticoid Receptor Deletion.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Endothelial Dysfunction in Pregnancy Complications.Biomedicines · 2021Review
- Article
- Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsiaFrontiers in cardiovascular medicine · 2021Article
- Reduced Microvascular Blood Volume as a Driver of Coronary Microvascular Disease in Patients With Non-obstructive Coronary Artery Disease: Rationale and Design of the MICORDIS Study.Frontiers in cardiovascular medicine · 2021Article
- Evaluation of Vascular Endothelial Function in Young and Middle-Aged Women with Respect to a History of Pregnancy, Pregnancy-Related Complications, Classical Cardiovascular Risk Factors, and Epigenetics.International journal of molecular sciences · 2020Article
- Predicting Preeclampsia with Noninvasive Measures of Endothelial Dysfunction: A Pilot Study.AJP reports · 2020Article
- Absent or Excessive Corpus Luteum Number Is Associated With Altered Maternal Vascular Health in Early Pregnancy.Hypertension (Dallas, Tex. : 1979) · 2019Article
- A Systematic Review of Vascular Structure and Function in Pre-eclampsia: Non-invasive Assessment and Mechanistic Links.Frontiers in cardiovascular medicine · 2019Review
- Correlation of CXCR4/CXCR7 signaling pathway with pre-eclampsia.Experimental and therapeutic medicine · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe EndoPAT method has been used as a non-invasive method for assessing endothelial function in several non-pregnant populations. We investigated its possible use in assessing endothelial dysfunction in pre-eclampsia.
methodsTwo hundred and fifteen participants were recruited and grouped as pre-eclamptic cases (105) and normotensive controls (110). Endothelial function and arterial stiffness were measured as reactive hyperaemia index and augmentation index, respectively, using the EndoPAT 2000 machine.
resultsThe reactive hyperaemia index was significantly lower in the pre-eclamptic group compared to the normotensive group (p < 0.05). Augmentation index on the other hand was significantly higher in the pre-eclamptic group compared to the normotensive group (p < 0.0001).
conclusionThe EndoPAT method demonstrates endothelial dysfunction and arterial stiffness in pre-eclampsia.
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Registered trials
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