Evidence map›Paper›PMID 27196400›Full record

ArticlePloS one2016

Cancer Incidence among Heart, Kidney, and Liver Transplant Recipients in Taiwan.

Kwai-Fong Lee, Yi-Ting Tsai, Chih-Yuan Lin, Chung-Bao Hsieh, Sheng-Tang Wu, Hung-Yen Ke, Yi-Chang Lin, Feng-Yen Lin, Wei-Hwa Lee, Chien-Sung Tsai

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Malignancy: An Adverse Effect of Immunosuppression.Handbook of experimental pharmacology · 2022
    Article
  4. Review
  5. Article
  6. Timing of mTORI usage and outcomes in kidney transplant recipients.International journal of medical sciences · 2021
    Observational
  7. History of cigarette smoking and heart transplant outcomes.International journal of cardiology. Heart & vasculature · 2020
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Kwai-Fong LeeGraduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.
Yi-Ting TsaiDivision of Cardiovascular Surgery, Tri-Service General Hospital, Taipei, Taiwan.
Chih-Yuan LinDivision of Cardiovascular Surgery, Tri-Service General Hospital, Taipei, Taiwan.
Chung-Bao HsiehDivision of General Surgery, Tri-Service General Hospital, Taipei, Taiwan.
Sheng-Tang WuDivision of Urology, Tri-Service General Hospital, Taipei, Taiwan.
Hung-Yen KeDivision of Cardiovascular Surgery, Tri-Service General Hospital, Taipei, Taiwan.
Yi-Chang LinDivision of Cardiovascular Surgery, Tri-Service General Hospital, Taipei, Taiwan.
Feng-Yen LinDepartment of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Wei-Hwa LeeDepartment of Pathology, Taipei Medical University Shuang-Ho Hospital, New Taipei, Taiwan.
Chien-Sung TsaiGraduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.
Tri-Service General Hospital · TWTaipei Medical University · TWTaipei Medical University Hospital · TWTaoyuan Armed Forces General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Population-based evidence of the relative risk of cancer among heart, kidney, and liver transplant recipients from Asia is lacking. The Taiwan National Health Insurance Research Database was used to conduct a population-based cohort study of transplant recipients (n = 5396), comprising 801 heart, 2847 kidney, and 1748 liver transplant recipients between 2001 and 2012. Standardized incidence ratios and Cox regression models were used. Compared with the general population, the risk of cancer increased 3.8-fold after heart transplantation, 4.1-fold after kidney transplantation and 4.6-fold after liver transplantation. Cancer occurrence showed considerable variation according to transplanted organs. The most common cancers in all transplant patients were cancers of the head and neck, liver, bladder, and kidney and non-Hodgkin lymphoma. Male recipients had an increased risk of cancers of the head and neck and liver, and female kidney recipients had a significant risk of bladder and kidney cancer. The adjusted hazard ratio for any cancer in all recipients was higher in liver transplant recipients compared with that in heart transplant recipients (hazard ratio = 1.5, P = .04). Cancer occurrence varied considerably and posttransplant cancer screening should be performed routinely according to transplanted organ and sex.

Indexed as

Heart TransplantationIncidenceKidney TransplantationLiver TransplantationAdolescentAdultChildChild, PreschoolCohort StudiesDatabases, FactualFemaleHeart FailureHumansInfantInfant, NewbornLiver Failure

Identifiers

PMID27196400
PMCPMC4873185
OpenAlexW2402574291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.