Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2016
Results of a Multilevel Intervention Trial to Increase Human Papillomavirus (HPV) Vaccine Uptake among Adolescent Girls.
Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 46 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - BootCamp Translation
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Pilot Trial
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Randomized Controlled Trial (RCT)
Who cites it
46 citing papers in PubMed, 10 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Factors that influence caregivers' and adolescents' views and practices regarding human papillomavirus (HPV) vaccination for adolescents: a qualitative evidence synthesis.The Cochrane database of systematic reviews · 2025Pooled it
- A systematic review and meta-analysis of strategies to promote vaccination uptake.Nature human behaviour · 2024Pooled it
- Community Engagement in Vaccination Promotion: Systematic Review and Meta-Analysis.JMIR public health and surveillance · 2024Pooled it
- A Systematic Review of the Effectiveness of Health Education Programs for Cervical Cancer Prevention in Rural Communities: Implications for Promoting Health Equity.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024Pooled it
- A systematic review of interventions to promote HPV vaccination globally.BMC public health · 2023Pooled it
- A narrative review of HPV vaccination interventions in rural U.S. communities.Preventive medicine · 2021Pooled it
- Increasing HPV Vaccination Uptake among Adolescents: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Improving vaccination uptake among adolescents.The Cochrane database of systematic reviews · 2020Pooled it
- Human Papillomavirus Vaccine Uptake, Knowledge, and Acceptance for Youth: A Systematic Review of Appalachia.Journal of community health · 2018Pooled it
- Patient reminder and recall interventions to improve immunization rates.The Cochrane database of systematic reviews · 2018Pooled it
- Implementation of quality improvement coaching versus physician communication training for improving human papillomavirus vaccination in primary care: a randomized implementation trial.Translational behavioral medicine · 2022Trial
- An Exploratory Study of Rural Parents' Knowledge and Attitudes About HPV Vaccination Following a Healthcare Visit With Their Child's Primary Care Provider.Journal of primary care & community healthTrial
- Evaluation of a Minigrant Program for Multilevel Interventions to Promote Human Papillomavirus Vaccination in Rural Communities in Georgia.Preventing chronic disease · 2026Article
- The Influence of Social Media Messaging on Human Papillomavirus Vaccine Attitudes and Confidence Among Adolescent Males: Group Discussion Study.JMIR cancer · 2026Article
- Review
- Evaluation of the reliability and validity of the health literacy scale for HPV vaccination among parents of girls aged 9-14.Human vaccines & immunotherapeutics · 2025Article
- Multilevel Interventions Aimed at Improving HPV Immunization Coverage: A Systematic Review and Meta-Analysis.Vaccines · 2025Review
- Health Equity and Human Papillomavirus Vaccine Interventions for Adolescents: A Systematic Review.Vaccines · 2025Review
- Review
- From multilevel to trans-level interventions: A critical next step for creating sustainable social change to improve mental health.The American journal of orthopsychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundUptake of the human papillomavirus (HPV) vaccine is low in Appalachian Ohio and areas with high cervical cancer rates.
methodsWe conducted a group-randomized trial among 12 counties in Appalachian Ohio randomized to receive either an HPV vaccine (intervention counties) or influenza vaccine (comparison counties) multilevel intervention (MLI). Parents (n = 337) who had a daughter aged 9 to 17 years who had not received the HPV vaccine were recruited from commercial lists. Clinics (N = 24) and 119 providers from these clinics were also recruited. The primary outcome was medical record-confirmed receipt of the first shot of the HPV vaccine 3 months after receiving the intervention among daughters of parents enrolled in the study. Secondary outcomes included receipt of the first HPV vaccine shot by 6 months and changes in provider knowledge.
resultsAccording to medical records, 10 (7.7%) daughters of intervention participants received the first shot of the HPV vaccine within 3 months of being sent the intervention materials compared with 4 (3.2%) daughters of comparison group participants (P = 0.061). By 6 months, 17 (13.1%) daughters of intervention participants received the first HPV vaccine shot compared with eight (6.5%) daughters of comparison group participants (P = 0.002). Provider knowledge about HPV increased (P < 0.001, from baseline to after education).
conclusionsThe MLI increased uptake of the HPV vaccine among girls aged 9 to 17 years; however, uptake was low. IMPACT: To improve HPV vaccine uptake, attention to additional levels of influence (e.g., policy, community) and more elements within levels (e.g., reminders, automated prompts) may be needed. Cancer Epidemiol Biomarkers Prev; 25(4); 593-602. ©2016 AACR SEE ALL ARTICLES IN THIS CEBP FOCUS SECTION, "MULTILEVEL APPROACHES TO ADDRESSING CANCER HEALTH DISPARITIES".
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.