Evidence map›Paper›PMID 27195957›Full record

Trial reportPloS one2016

Household HIV Testing Uptake among Contacts of TB Patients in South Africa.

Kavindhran Velen, James J Lewis, Salome Charalambous, Liesl Page-Shipp, Flora Popane, Gavin J Churchyard, Christopher J Hoffmann

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Determining the value of TB active case-finding: current evidence and methodological considerations.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2021
    Article
  11. Quality matters: Redefining child TB care with an emphasis on quality.Journal of clinical tuberculosis and other mycobacterial diseases · 2019
    Article
  12. Article
  13. HIV testing uptake among the household contacts of multidrug-resistant tuberculosis index cases in eight countries.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Kavindhran VelenThe Aurum Institute, Johannesburg, South Africa.
James J LewisLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Salome CharalambousThe Aurum Institute, Johannesburg, South Africa.
Liesl Page-ShippThe Aurum Institute, Johannesburg, South Africa.
Flora PopaneThe Aurum Institute, Johannesburg, South Africa.
Gavin J ChurchyardThe Aurum Institute, Johannesburg, South Africa.
Christopher J HoffmannThe Aurum Institute, Johannesburg, South Africa.
Aurum Institute · ZALondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MR/K007467/1
6 · The paper itself

Abstract

backgroundIn high HIV prevalence settings, offering HIV testing may be a reasonable part of contact tracing of index tuberculosis (TB) patients. We evaluated the uptake of HIV counselling and testing (HCT) among household contacts of index TB patients and the proportion of newly diagnosed HIV-infected persons linked into care as part of a household TB contact tracing study.

methodsWe recruited index TB patients at public health clinics in two South African provinces to obtain consent for household contact tracing. During scheduled household visits we offered TB symptom screening to all household members and HCT to individuals ≥14years of age. Factors associated with HCT uptake were investigated using a random effects logistic regression model. RESULTS & DISCUSSION: Out of 1,887 listed household members ≥14 years old, 984 (52%) were available during a household visit and offered HCT of which 108 (11%) self-reported being HIV infected and did not undergo HCT. Of the remaining 876, a total of 304 agreed to HCT (35%); 26 (8.6%) were newly diagnosed as HIV positive. In multivariable analysis, factors associated with uptake of HCT were prior testing (odds ratio 1.6; 95% confidence interval [CI]: 1.1-2.3) and another member in the household testing (odds ratio 2.4; 95% CI: 1.7-3.4). Within 3 months of testing HIV-positive, 35% reported initiating HIV care.

conclusionHCT as a component of household TB contact tracing reached individuals without prior HIV testing, however uptake of HIV testing was poor. Strategies to improve HIV testing in household contacts should be evaluated.

Indexed as

AdolescentAdultCD4-Positive T-LymphocytesCluster AnalysisContact TracingFamily CharacteristicsFemaleHIV InfectionsHumansIsoniazidMaleMass ScreeningMiddle AgedMultivariate AnalysisOdds RatioPrevalenceIsoniazid

Identifiers

PMID27195957
PMCPMC4873208
OpenAlexW2403655087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.