ArticlePloS one2016
Antioxidant Potential of Vespa affinis L., a Traditional Edible Insect Species of North East India.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 61 citations in OpenAlex.
- Antioxidant Potential of Schistocerca gregaria (Orthoptera: Acrididae) Extract: HPLC Analysis, Molecular Docking, and Bioassays.Chemistry & biodiversity · 2026Article
- The use of edible insects in human food.Journal of the science of food and agriculture · 2026Review
- Phytochemical analysis of leaf extract of Piper nigrum and investigation of its biological activities.Inflammopharmacology · 2025Article
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- Entomophagy and entomo-therapeutic practices in a mountainous territory in southeast Guangxi Zhuang Autonomous Region, China.Journal of ethnobiology and ethnomedicine · 2024Article
- Ethno-entomotherapeutic and metabolite profiling of Coridius chinensis (Dallas), a traditional edible insect species of North-East India.Scientific reports · 2024Article
- Bio-economic potential of ethno-entomophagy and its therapeutics in India.NPJ science of food · 2024Review
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- Edible Insects in Thailand: An Overview of Status, Properties, Processing, and Utilization in the Food Industry.Foods (Basel, Switzerland) · 2023Review
- Review
- Growth, Biochemical Characteristics, Flesh Quality, and Gut Microbiota of the Pacific White Shrimp (Aquaculture nutrition · 2023Article
- QSAR study of phenolic compounds and their anti-DPPH radical activity by discriminant analysis.Scientific reports · 2022Article
- Oriental Hornet (Molecules (Basel, Switzerland) · 2021Article
- Stewardship of Wild and Farmed Edible Insects as Food and Feed in Sub-Saharan Africa: A Perspective.Frontiers in veterinary science · 2021Review
- Dietary Modulation of Oxidative Stress From Edible Insects: A Mini-Review.Frontiers in nutrition · 2021Review
- Enhanced Antioxidant and Cytotoxic Potentials of Lipopolysaccharides-InjectedPharmaceutics · 2020Article
- Effect of Thermal Processing on Physico-Chemical and Antioxidant Properties in Mulberry Silkworm (Foods (Basel, Switzerland) · 2020Article
- Ferric-bipyridine assay: A novel spectrophotometric method for measurement of antioxidant capacity.Heliyon · 2020Article
- Insights into the Allergenic Potential of the Edible Yellow Mealworm (Foods (Basel, Switzerland) · 2019Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionElevated oxidative stress plays an important role in the pathogenesis of health disorders, like arthritis. Traditionally, Vespa affinis L., a common edible insect among many tribes in North-East India, is believed to have a beneficial role in extenuating health disorders, such as arthritis. The present study investigated the molecular mechanism underlying medicinal benefit of the Aqueous Extract of Vespa affinis L. (AEVA) against oxidative stress pathophysiology.
methodsThe free radical scavenging activities of AEVA were examined against DPPH, hydroxyl, and superoxide radicals and the effect on the activities of antioxidant enzyme (GST and CAT) was determined using both recombinant proteins and human plasma. The antioxidant potential of AEVA was again investigated using THP-1 monocytes.
resultsAEVA possesses a significant free radical scavenging activity as evident from the DPPH, superoxide, and hydroxyl radical scavenging assay. Incubation of AEVA (2.5, 5, 7.5, and 10 μg/μL) with the recombinant antioxidant enzymes, rGST and rCAT significantly increased the enzyme activities compared to those observed in corresponding enzyme alone or AEVA itself. AEVA supplementation (5, 7.5, and 10 μg/μL) also stimulates the activities of GST and CAT when incubated with human plasma. A cell culture study also confirmed the beneficial role of AEVA (0.8 and 1.2 μg/μL) which enhances the activities of GST and CAT, and also reduces the intercellular ROS production in monocytes treated with or without H2O2 and the effects are at par with what is observed in N-acetyl cysteine-treated cells.
conclusionThe antioxidant potential of the aqueous extract of Vespa affinis L. may mediate its therapeutic activities in oxidative stress-associated health disorders.
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