ReviewPulse (Basel, Switzerland)2016
Hyperuricemia, Cardiovascular Disease, and Hypertension.
Review in Pulse (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 169 citations in OpenAlex.
- Uric acid lowering improves insulin sensitivity and lowers blood pressure: a meta-analysis of randomized parallel-controlled clinical trials.African health sciences · 2021Pooled it
- Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review.Biosensors · 2020Pooled it
- High serum uric acid levels may increase mortality and major adverse cardiovascular events in patients with acute myocardial infarction.Saudi medical journal · 2017Pooled it
- Efficacy and Safety of Allisartan Isoproxil/Amlodipine in Patients with Essential Hypertension: A Phase III, Multicenter, Double-Blind, Parallel-Group, Randomised study.Journal of human hypertension · 2025Trial
- Efficacy and Safety of Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled by Amlodipine: A Phase III, Multicenter, Double-Blind, Parallel-Group, Randomized Controlled Trial.Journal of clinical hypertension (Greenwich, Conn.) · 2025Trial
- Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease.EBioMedicine · 2018Trial
- Effect of allopurinol on the glomerular filtration rate of children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2018Trial
- Prevalence of hyperuricemia among patients with non-communicable diseases in Ethiopia: a systematic review and meta-analysis.Cardiovascular diabetology. Endocrinology reports · 2026Review
- Exploring Uric Acid to HDL Ratio as a Long-Term Biomarker for Diabetes Mellitus.Journal of clinical laboratory analysis · 2026Article
- From Multidimensional Management to Mechanistic Insight: A Review of Interventions for Hyperuricemia.International journal of molecular sciences · 2026Review
- Serum uric acid and its association with general and abdominal obesity and elevated blood pressure among young adults in Sylhet division, Bangladesh.BMC endocrine disorders · 2026Article
- Sex-Specific Association of Drinking Habit and Alcohol Beverage Type With Serum Uric Acid in a Healthy Population.Journal of Korean medical science · 2026Article
- Serum Uric Acid and Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus: A Cross-Sectional Study From Northeastern Tanzania.Journal of diabetes research · 2026Article
- Article
- Association of uric acid to high-density cholesterol ratio (UHR) with biological age acceleration: evidence from NHANES 2009-2018.Scientific reports · 2025Article
- Hyperuricemia-induced kidney injury: a narrative review of mechanisms and therapeutic advances.BMC nephrology · 2025Review
- Serum Biochemical Markers and Rheumatoid Arthritis: Insights From Observational Study and Mendelian Randomization Analysis.International journal of rheumatic diseases · 2025Article
- The Impact of Hyperuricemia on the Progression of Atherosclerotic Cardiovascular Disease.Cureus · 2025Article
- Hyperuricemia in Chronic Kidney Disease: Emerging Pathophysiology and a Novel Therapeutic Strategy.International journal of molecular sciences · 2025Review
- THE ASSOCIATION OF SYNTAX SCORE II WITH LIPID PROFILE, SERUM URIC ACID LEVELS AND DIABETES MELLITUS IN PATIENTS WITH MULTIVESSEL CORONARY DISEASE.Acta clinica Croatica · 2025Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, there has been an increase in the prevalence of hyperuricemia, and the latter has attracted attention as an adult lifestyle-associated disease, together with hypertension, diabetes, and dyslipidemia. Although hyperuricemia is known to be an independent risk factor for hypertension, whether it is an independent risk factor for cardiovascular disease remains controversial. Recently, some small-scale interventional studies on antihyperuricemic medications showed that the latter improved angina symptoms and prevented cardiovascular disease. Here, we will mainly explain the cause of hyperuricemia and the associations between hyperuricemia, hypertension, and cardiovascular disease based on the latest published evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.