Evidence map›Paper›PMID 27195068›Full record

ArticleCommunicative & integrative biology

The foundations of cross-modal plasticity.

Ithai Rabinowitch, Jihong Bai

Open access · goldAbstract read
In one paragraph

Article in Communicative & integrative biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  9. 5-HTRMolecular brain · 2018
    Article
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  11. Visual experience sculpts whole-cortex spontaneous infraslow activity patterns through an Arc-dependent mechanism.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ithai RabinowitchDivision of Basic Sciences, Fred Hutchinson Cancer Research Center , Seattle, WA, USA.
Jihong BaiDivision of Basic Sciences, Fred Hutchinson Cancer Research Center , Seattle, WA, USA.
Fred Hutch Cancer Center · US

Funding

Membrane Bending Machinery for Synaptic Vesicle EndocytosisR01NS085214 · NINDS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAI, JIHONG · 2013 to 2017
$1.9M
NINDS NIH HHS R01 NS085214
6 · The paper itself

Abstract

Cross-modal plasticity is a striking adaptive feature of the brain, whereby the loss of one sensory modality induces cortical reorganization that leads to enhanced sensory performance in remaining modalities. Much is known about the macroscopic modifications in the brain that underly cross-modal plasticity and the associated changes in sensory performance. In contrast there is relatively scant information about the molecular and cellular underpinnings of this mechanism. We hypothesized that cross-modal plasticity is a fundamental feature of the nervous system. As such, it should be found in organisms with brains that are substantially less complex than our own. Indeed, we discovered a cross-modal plasticity mechanism in the roundworm Caenorhabditis elegans, whose nervous system is composed of only 302 neurons. Taking advantage of the simplicity of the C. elegans nervous system, we were able to comprehensively study cross-modal plasticity from molecule through circuit to behavior.

Indexed as

caenorhabditis eleganscalcium imagingcross-modal plasticitymechanosensationneuropeptideolfactionoptogeneticssynaptic engineering

Identifiers

PMID27195068
PMCPMC4857785
OpenAlexW2335794781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.