ArticleInternational journal of nanomedicine2016
Voltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products.
Article in International journal of nanomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 79 citations in OpenAlex.
- Development of a Horseradish Peroxidase-Based Electrochemical Biosensor for Melatonin Detection.Biosensors · 2026Article
- Juglone/MWCNT-Modified Electrode for High-Performance Melatonin Detection.International journal of molecular sciences · 2026Article
- Article
- Electrochemical Detection of Melatonin in the Presence of Dopamine on a Ce-Doped Poly(bromocresol purple)-Modified Electrode.ACS omega · 2025Article
- Eco-friendly spectrofluorimetric and HPLC-fluorescence methods for simultaneous determination of melatonin and zolpidem in pharmaceuticals.Scientific reports · 2025Article
- A Zinc Oxide Interconnected Hydroxypropyl-Beta-Cyclodextrin/rGO Nanocomposite as an Electrocatalyst for Melatonin Detection: An Ultra-Sensitive Electrochemical Sensor.Sensors (Basel, Switzerland) · 2025Article
- Carbon-Nanotube Microelectrodes for Electrochemical Determination of Melatonin.Electroanalysis · 2024Article
- Ruthenium-Anchored Carbon Sphere-Customized Sensor for the Selective Amperometric Detection of Melatonin.Biosensors · 2023Article
- Development of a Chemically Modified Sensor Based on a Pentapeptide and Its Application for Sensitive Detection of Verbascoside in Extra Virgin Olive Oil.International journal of molecular sciences · 2022Article
- Advances on Hormones and Steroids Determination: A Review of Voltammetric Methods since 2000.Membranes · 2022Review
- Tyrosinase-Based Biosensor-A New Tool for Chlorogenic Acid Detection in Nutraceutical Formulations.Materials (Basel, Switzerland) · 2022Article
- A Sensitive Electrochemical Sensor Based on Sonogel-Carbon Material Enriched with Gold Nanoparticles for Melatonin Determination.Sensors (Basel, Switzerland) · 2021Article
- Voltammetric Determination of Levodopa Using Mesoporous Carbon-Modified Screen-Printed Carbon Sensors.Sensors (Basel, Switzerland) · 2021Article
- Development of a Novel Electrochemical Biosensor Based on Carbon Nanofibers-Cobalt Phthalocyanine-Laccase for the Detection of p-Coumaric Acid in Phytoproducts.International journal of molecular sciences · 2021Article
- Electrochemical Determination of Chlorogenic Acid in Nutraceuticals Using Voltammetric Sensors Based on Screen-Printed Carbon Electrode Modified with Graphene and Gold Nanoparticles.International journal of molecular sciences · 2021Article
- Determination of Diosmin in Pharmaceutical Products with Chemically Modified Voltammetric Sensors.International journal of molecular sciences · 2021Article
- Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review.International journal of molecular sciences · 2021Review
- Recent Advances in Electrochemical and Optical Sensors for Detecting Tryptophan and Melatonin.International journal of nanomedicine · 2021Review
- Voltamperometric Sensors and Biosensors Based on Carbon Nanomaterials Used for Detecting Caffeic Acid-A Review.International journal of molecular sciences · 2020Review
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melatonin can be sensitively detected in pharmaceuticals by cyclic voltammetry and fixed-potential amperometry using a graphene-based sensor. The sensor characterization of cyclic voltammetry constantly provides high values of electrode active area and heterogeneous rate constant. In optimal conditions, the sensor was applied for the determination of melatonin in different pharmaceutical samples. The sensitivity to melatonin was 0.0371 A M(-1), and the limit of detection was 0.87×10(-6) M. The data obtained by using the graphene-based sensor for the detection of melatonin in pharmaceutical products were in good agreement with the data provided by the producer. Since no interferences from the excipients were found, using a separation technique was not necessary. Additionally, the low price, ease of handling, small amount of sample, short time per analysis, and possibility of automation are the important advantages that recommend this methodology for quality control of pharmaceuticals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.