ArticleInternational journal of chronic obstructive pulmonary disease2016
Vital capacity and COPD: the Swedish CArdioPulmonary bioImage Study (SCAPIS).
Article in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 42 citations in OpenAlex.
- Occupational exposures and risk of pulmonary alveolar proteinosis (PAP).Scandinavian journal of work, environment & health · 2026Article
- Health status and prognosis of COPD patients in relation to the FEVNPJ primary care respiratory medicine · 2026Article
- Lung nodule localization and size estimation on chest tomosynthesis.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Chronic Airflow Limitation, Emphysema, and Impaired Diffusing Capacity in Relation to Smoking Habits in a Swedish Middle-aged Population.Annals of the American Thoracic Society · 2024Article
- Article
- Pulmonary Function Tests: Easy Interpretation in Three Steps.Journal of clinical medicine · 2024Review
- Clinical relevance of lung function trajectory clusters in middle-aged and older adults.ERJ open research · 2024Article
- Occupational risks for infection with influenza A and B: a national case-control study covering 1 July 2006-31 December 2019.Occupational and environmental medicine · 2023Article
- The Role of Pulmonary Function Testing in the Diagnosis and Management of COPD.Respiratory care · 2023Review
- Ever Smoking is Not Associated with Performed Spirometry while Occupational Exposure and Respiratory Symptoms are.International journal of chronic obstructive pulmonary disease · 2023Article
- Ratio of FEVChest · 2021Observational
- The ratio FEVClinical physiology and functional imaging · 2021Article
- Inhaled Corticosteroids Use and Risk of Invasive Pneumococcal Disease in a Population-based Study.Annals of the American Thoracic Society · 2020Article
- Underlying contributing conditions to breathlessness among middle-aged individuals in the general population: a cross-sectional study.BMJ open respiratory research · 2020Article
- Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study.BMJ open respiratory research · 2020Article
- Restrictive spirometric pattern and true pulmonary restriction in a general population sample aged 50 - 64 years.BMC pulmonary medicine · 2020Article
- Occupational exposure to dust and to fumes, work as a welder and invasive pneumococcal disease risk.Occupational and environmental medicine · 2020Article
- Clinical and functional correlations of the difference between slow vital capacity and FVC.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2020Article
- Joint Indian Chest Society-National College of Chest Physicians (India) guidelines for spirometry.Lung India : official organ of Indian Chest Society · 2019Article
- Absolute lung size and the sex difference in breathlessness in the general population.PloS one · 2018Article
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Authors and funding
19 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSpirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value <0.7 or below the lower limit of normal (LLN). Forced vital capacity (FVC) is a proxy for VC. The first aim was to compare the use of FVC and VC, assessed as the highest value of FVC or slow vital capacity (SVC), when assessing the FEV1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC.
methodsSubjects (n=1,050) aged 50-64 years were investigated with FEV1, FVC, and SVC after bronchodilation. Global Initiative for Chronic Obstructive Lung Disease (GOLD) COPDFVC was defined as FEV1/FVC <0.7, GOLDCOPDVC as FEV1/VC <0.7 using the maximum value of FVC or SVC, LLNCOPDFVC as FEV1/FVC below the LLN, and LLNCOPDVC as FEV1/VC below the LLN using the maximum value of FVC or SVC.
resultsPrevalence of GOLDCOPDFVC was 10.0% (95% confidence interval [CI] 8.2-12.0) and the prevalence of LLNCOPDFVC was 9.5% (95% CI 7.8-11.4). When estimates were based on VC, the prevalence became higher; 16.4% (95% CI 14.3-18.9) and 15.6% (95% CI 13.5-17.9) for GOLDCOPDVC and LLNCOPDVC, respectively. The group of additional subjects classified as having COPD based on VC, had lower FEV1, more wheeze and higher residual volume compared to subjects without any COPD.
conclusionThe prevalence of COPD was significantly higher when the ratio FEV1/VC was calculated using the highest value of SVC or FVC compared with using FVC only. Subjects classified as having COPD when using the VC concept were more obstructive and with indications of air trapping. Hence, the use of only FVC when assessing airflow limitation may result in a considerable under diagnosis of subjects with mild COPD.
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