ReviewClinical interventions in aging2016
Hospitalization in older patients due to adverse drug reactions -the need for a prediction tool.
Review in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05589870 (A Retrospective, Comparative Study, for the Assessment of a Novel System, an Algorithm for Medication Safety and Consultation for Chronic Polypharmacy Patients), which is not on this map. Cited by 69 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Retrospective, Comparative Study, for the Assessment of a Novel System, an Algorithm for Medication Safety and Consultation for Chronic Polypharmacy Patients
Who cites it
69 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of and Risk Factors for Drug-Related Readmissions in Older Adults: A Systematic Review and Meta-Analysis.Drugs & aging · 2024Pooled it
- Systematic review of predictive risk models for adverse drug events in hospitalized patients.British journal of clinical pharmacology · 2018Pooled it
- Reducing Adverse Drug Reactions for Older People in the Community: Evaluating the Validity and Reliability of the ADRe Profile.Journal of nursing management · 2025Trial
- ABCG2 Genetic Variability in Drug Exposure and Toxicity: Implications for Clinical Practice.Toxics · 2026Review
- Implied ADR-Admissions: A Cohort Study Introducing a Novel Administrative Data Approach for Identifying Drug-Related Hospitalisations.Drug safety · 2026Article
- The other side of the coin: The case for deprescribing competencies in medical education.Canadian family physician Medecin de famille canadien · 2026Article
- Predicting clozapine-induced adverse drug reaction biomarkers using machine learning.Scientific reports · 2025Article
- The impact of potentially inappropriate medicines on adverse clinical outcomes in the aged: A retrospective cohort study.Exploratory research in clinical and social pharmacy · 2025Article
- The impact of polypharmacy on health outcomes in the aged: A retrospective cohort study.PloS one · 2025Article
- Article
- Clinical reasoning in pharmacy: What do eye movements and verbal protocols tell us about the processing of a case task?Advances in health sciences education : theory and practice · 2024Article
- Adverse Events Associated With Disease-Modifying Drugs for Multiple Sclerosis: A Multiregional Population-Based StudyNeurology · 2024Article
- Assessing Clinical Utility of Pharmacogenetic Testing in the Military Health System.Military medicine · 2024Article
- Potentially Inappropriate Prescribing and Potential Prescribing Omissions and Their Association with Adverse Drug Reaction-Related Hospital Admissions.Journal of clinical medicine · 2024Article
- A Comparative Study Assessing the Incidence and Degree of Hyperkalemia in Patients on Unfractionated Heparin versus Low-Molecular Weight Heparin.Clinical pharmacology : advances and applications · 2024Article
- Costs associated with adverse drug reactions in an older population admitted to hospital: a prospective cohort study.European journal of clinical pharmacology · 2023Article
- Exploring Australian pharmacists' perceptions and practices towards reducing the risk of medicines-related harm in aged care residents.Frontiers in pharmacology · 2023Article
- Adverse drug events in Chinese elder inpatients: a retrospective review for evaluating the efficiency of the Global Trigger Tool.Frontiers in medicine · 2023Article
- Using PIM-Taiwan, PRISCUS, and Beers criteria to assess potentially inappropriate medication use among older adults with 90-day rehospitalization: a population-based study in Taiwan.Frontiers in pharmacology · 2023Article
- A novel strategy to optimize critical information on over the counter labels for older adults.Health science reports · 2023Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adverse drug reactions (ADRs) represent a major burden on society, resulting in significant morbidity, mortality, and health care costs. Older patients living in the community are particularly susceptible to ADRs, and are at an increased risk of ADR-related hospitalization. This review summarizes the available evidence on ADR-related hospital admission in older patients living in the community, with a particular focus on risk factors for ADRs leading to hospital admission and the need for a prediction tool for risk of ADR-related hospitalization in these individuals. The reported proportion of hospital admissions due to ADRs has ranged from 6% to 12% of all admissions in older patients. The main risk factors or predictors for ADR-related admissions were advanced age, polypharmacy, comorbidity, and potentially inappropriate medications. There is a clear need to design intervention strategies to prevent ADR-related hospitalization in older patients. To ensure the cost-effectiveness of such strategies, it would be necessary to target them to those older individuals who are at highest risk of ADR-related hospitalization. Currently, there are no validated tools to assess the risk of ADRs in primary care. There is a clear need to investigate the utility of tools to identify high-risk patients to target appropriate interventions toward prevention of ADR-related hospital admissions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.