ArticleLearning & memory (Cold Spring Harbor, N.Y.)2016
Motivational state, reward value, and Pavlovian cues differentially affect skilled forelimb grasping in rats.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Deep Brain Stimulation of the Subthalamic Nucleus Modulates Reward-Related Behavior: A Systematic Review.Frontiers in human neuroscience · 2020Pooled it
- Revealing abrupt transitions from goal-directed to habitual behavior.Nature communications · 2026Article
- Lizards and tortoises show evidence of low inhibitory control.Scientific reports · 2025Article
- Consensus Paper: Cerebellum and Reward.Cerebellum (London, England) · 2024Review
- Sex differences in neural representations of social and nonsocial reward in the medial prefrontal cortex.Nature communications · 2024Article
- Effects of reward and effort history on decision making and movement vigor during foraging.Journal of neurophysiology · 2024Article
- Task-Related Differences in End-Point Kinematics in School-Age Children with Typical Development.Behavioral sciences (Basel, Switzerland) · 2023Article
- Endogenous dopamine transmission is crucial for motor skill recovery after stroke.IBRO neuroscience reports · 2022Article
- Selective behavioural impairments in mice heterozygous for the cross disorder psychiatric risk gene DLG2.Genes, brain, and behavior · 2022Article
- Sequential reversal learning: a new touchscreen schedule for assessing cognitive flexibility in mice.Psychopharmacology · 2021Article
- Deliberative Decision-Making in Macaques Removes Reward-Driven Response Vigor.Frontiers in behavioral neuroscience · 2021Article
- An automated homecage system for multiwhisker detection and discrimination learning in mice.PloS one · 2020Article
- Following of aging process in a new motor skill learning model, "pot jumping" in rats.GeroScience · 2019Article
- Vigor of reaching movements: reward discounts the cost of effort.Journal of neurophysiology · 2018Article
- Circuit changes in motor cortex during motor skill learning.Neuroscience · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Motor skills represent high-precision movements performed at optimal speed and accuracy. Such motor skills are learned with practice over time. Besides practice, effects of motivation have also been shown to influence speed and accuracy of movements, suggesting that fast movements are performed to maximize gained reward over time as noted in previous studies. In rodents, skilled motor performance has been successfully modeled with the skilled grasping task, in which animals use their forepaw to grasp for sugar pellet rewards through a narrow window. Using sugar pellets, the skilled grasping task is inherently tied to motivation processes. In the present study, we performed three experiments modulating animals' motivation during skilled grasping by changing the motivational state, presenting different reward value ratios, and displaying Pavlovian stimuli. We found in all three studies that motivation affected the speed of skilled grasping movements, with the strongest effects seen due to motivational state and reward value. Furthermore, accuracy of the movement, measured in success rate, showed a strong dependence on motivational state as well. Pavlovian cues had only minor effects on skilled grasping, but results indicate an inverse Pavlovian-instrumental transfer effect on movement speed. These findings have broad implications considering the increasing use of skilled grasping in studies of motor system structure, function, and recovery after injuries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.