ArticleProceedings. Biological sciences2016
The peripheral olfactory code in Drosophila larvae contains temporal information and is robust over multiple timescales.
Article in Proceedings. Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Genetic and behavioral analyses suggest that larval and adult stages of Lucilia cuprina employ different sensory systems to detect rotten beef.Parasites & vectors · 2025Article
- Receptors underlying an odorant's valence across concentrations in Drosophila larvae.The Journal of experimental biology · 2024Article
- Sequence-Based Prediction of Olfactory Receptor Responses.Chemical senses · 2019Article
- Structured Odorant Response Patterns across a Complete Olfactory Receptor Neuron Population.Neuron · 2019Article
- Neuronal Response Latencies Encode First Odor Identity Information across Subjects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Behavior Responses to Chemical and Optogenetic Stimuli inFrontiers in behavioral neuroscience · 2018Article
- Take time: odor coding capacity across sensory neurons increases over time in Drosophila.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017Article
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Authors and funding
5 authors.
Funding
Abstract
We studied the electrophysiological activity of two classes of Drosophila melanogaster larval olfactory sensory neurons (OSNs), Or24a and Or74a, in response to 1 s stimulation with butanol, octanol, 2-heptanone, and propyl acetate. Each odour/OSN combination produced unique responses in terms of spike count and temporal profile. We used a classifier algorithm to explore the information content of OSN activity, and showed that as well as spike count, the activity of these OSNs included temporal information that enabled the classifier to accurately identify odours. The responses of OSNs during continuous odour exposure (5 and 20 min) showed that both types of neuron continued to respond, with no complete adaptation, and with no change to their ability to encode temporal information. Finally, we exposed larvae to octanol for 3 days and found only minor quantitative changes in OSN response to odours, indicating that the larval peripheral code is robust when faced with long-term exposure to odours, such as would be found in a natural context.
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Registered trials
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