ReviewPediatric nephrology (Berlin, Germany)2017
Potassium: friend or foe?
Review in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Potassium Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials.Journal of the American Heart Association · 2020Pooled it
- The use of minerals, plants and burnt materials in ancient medicine: Approaches to working recipes in John the Physician'sProceedings of the Geologists' Association. Geologists' Association · 2026Article
- The exquisite link between potassium homeostasis regulation and cardiovascular health: exploration and analysis.Frontiers in physiology · 2026Review
- Determination of Tissue Potassium and Sodium Concentrations in Dystrophic Skeletal Muscle Tissue Using Combined Potassium (NMR in biomedicine · 2025Article
- Article
- Article
- Prevalence and Related Factors of Hypokalemia in Patients with Acute Ischemic Stroke.International journal of general medicine · 2024Article
- Electrolyte Imbalance and Neurologic Injury.CNS & neurological disorders drug targets · 2024Review
- Review
- Serum Elemental Analysis of Type 2 Diabetes Patients Using SRXRF.Biological trace element research · 2022Article
- Pulse-based cropping systems for soil health restoration, resources conservation, and nutritional and environmental security in rainfed agroecosystems.Frontiers in microbiology · 2022Review
- Metal ions leachables from fake orthodontic braces incubated in simulated body fluid.BMC oral health · 2021Article
- Electrolytes and clinical outcomes in patients with acute ischemic stroke or transient ischemic attack.Annals of translational medicine · 2021Article
- Extravasation of Concentrated Potassium Chloride: A Case Report.Current therapeutic research, clinical and experimental · 2021Article
- WNK4 kinase is a physiological intracellular chloride sensor.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Association of soil potassium and sodium concentrations with spatial disparities of prevalence and mortality rates of hypertensive diseases in the USA.Environmental geochemistry and health · 2018Article
- Sodium and potassium urinary excretion and their ratio in the elderly: results from the Nutrition UP 65 study.Food & nutrition research · 2018Article
- Essential role of Kir5.1 channels in renal salt handling and blood pressure control.JCI insight · 2017Article
- Effect of Hypokalemia on Functional Outcome at 3 Months Post-Stroke Among First-Ever Acute Ischemic Stroke Patients.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The kidney plays an essential role in maintaining homeostasis of ion concentrations in the blood. Because the concentration gradient of potassium across the cell membrane is a key determinant of the membrane potential of cells, even small deviations in serum potassium level from the normal setpoint can lead to severe muscle dysfunction, resulting in respiratory failure and cardiac arrest. Less severe hypo- and hyperkalemia are also associated with morbidity and mortality across various patient populations. In addition, deficiencies in potassium intake have been associated with hypertension and adverse cardiovascular and renal outcomes, likely due in part to the interrelated handling of sodium and potassium by the kidney. Here, data on the beneficial effects of potassium on blood pressure and cardiovascular and renal outcomes will be reviewed, along with the physiological basis for these effects. In some patient populations, however, potassium excess is deleterious. Risk factors for the development of hyperkalemia will be reviewed, as well as the risks and benefits of existing and emerging therapies for hyperkalemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.